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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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COX-2-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
PTEROSTILBENE IC50=84 uM *
PUNICIC-ACID *
QUERCETIN <40 uM *
RESVERATROL >2.5->22.5 uM *
RESVERATROL 50 uM/ *
RESVERATROL 30 uM/ Subbaramaiah, K., Michaluart, P., Chung, W. J., Dannenberg, A. J. 1998. Resveratrol Inhibits the Expression of Cyclooxygenase-2 in Human Mammary and Oral Epithelial Cells. Pharm. Biol. Suppl., 36: 35-43.
ROSMARINIC-ACID IC>58=1,000 uM *
RUTAECARPINE 2.5 ug/ml (strong activity) Kang, S. S., Kim, J. S., Son, K. H., Kim, H. P., Chang, H. W. 1999. Cyclooxygenase-2 Inhibitor from Evodia rutaecarpa. Nat. Prod. Sci., 5(2): 65-69.
SALICYLIC-ACID Newmark, T. M. and Schulick, P. 2000. Herbal Cox-2 Inhibition - Nature's Challenge to Arthritis, Cancer & Alzheimer's Disease. Hohm Press, Prescott AZ.
TRANS-RESVERATROL 20 uM/ Jang, M., Pezzuto, J. M. 1999. Cancer Chemorpreventive Activity of Resveratrol. Drugs Exp. Clin. Res., 25(2/3): 65-77.
UROLITHIN-A *
URSOLIC-ACID IC50=130 uM/ *
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List of Activity Plants.
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Plant Name Common Name Chemical Count Total Parts Per Million
Barosma betulina Buchu 1 0
Basella alba Vinespinach 2 695
Benincasa hispida Waxgourd 1 2.5
Berberis vulgaris Barberry 6 253, 300
Bertholletia excelsa Brazilnut; Brazilnut-Tree; Creamnut; Paranut 1 0
Beta vulgaris Beet; Beetroot; Sugar Beet; Garden Beet 5 1, 752
Betula lenta Cherry Birch 1 0
Bidens pilosa 1 0
Bixa orellana Achiote; Annatto; Annato; Lipsticktree; Lipstick Pod; Bija; Annoto; Arnato 2 904
Blighia sapida Akee; Seso Vegetal 1 36
Boehmeria nivea Ramie 2 403
Borago officinalis Borage; Beebread; Beeplant; Talewort 4 31, 440
Boronia megastigma Scented Boronia 1 0
Boswellia sacra Olibanum; Frankincense; Olibanum Tree; Weihrauchbaum (Ger.); Weihrauchpflanze (Ger.); arbol del incensio (Sp.); Oliban (Sp.) 1 746.8999786376953
Boswellia serrata Salaki; Salai Guggal; Kundur Luban; Salai; Indian Olibanum-Tree; Indian Frankincense 3 0
Brassica chinensis Chinese Cabbage; Pak-Choi; Chinese Mustard; Bok-Choy; Celery Mustard; Chinese White Cabbage; Celery Cabbage 1 2, 695
Brassica napus var. napobrassica Rutabaga; Swede; Swedish Turnip 1 0
Brassica nigra Black Mustard 2 475
Brassica oleracea Kohlrabi 3 102.67000007629395
Brassica oleracea var. botrytis l. Cauliflower 5 186