An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
  1. Home
  2. COX-2-Inhibitor

COX-2-Inhibitor

Select a Results View:

Download these results as:
CSV
EXCEL
PDF
List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
PTEROSTILBENE IC50=84 uM *
PUNICIC-ACID *
QUERCETIN <40 uM *
RESVERATROL 30 uM/ Subbaramaiah, K., Michaluart, P., Chung, W. J., Dannenberg, A. J. 1998. Resveratrol Inhibits the Expression of Cyclooxygenase-2 in Human Mammary and Oral Epithelial Cells. Pharm. Biol. Suppl., 36: 35-43.
RESVERATROL >2.5->22.5 uM *
RESVERATROL 50 uM/ *
ROSMARINIC-ACID IC>58=1,000 uM *
RUTAECARPINE 2.5 ug/ml (strong activity) Kang, S. S., Kim, J. S., Son, K. H., Kim, H. P., Chang, H. W. 1999. Cyclooxygenase-2 Inhibitor from Evodia rutaecarpa. Nat. Prod. Sci., 5(2): 65-69.
SALICYLIC-ACID Newmark, T. M. and Schulick, P. 2000. Herbal Cox-2 Inhibition - Nature's Challenge to Arthritis, Cancer & Alzheimer's Disease. Hohm Press, Prescott AZ.
TRANS-RESVERATROL 20 uM/ Jang, M., Pezzuto, J. M. 1999. Cancer Chemorpreventive Activity of Resveratrol. Drugs Exp. Clin. Res., 25(2/3): 65-77.
UROLITHIN-A *
URSOLIC-ACID IC50=130 uM/ *
Download these results as:
CSV
EXCEL
PDF
List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Arracacia xanthorrhiza Arracacha; Peruvian Carrot 1 7.599999904632568
Artemisia abrotanum Southernwood 1 0
Artemisia absinthium Wormwood 2 500
Artemisia annua Qinghao; Sweet Annie; Annual Mugwort (GRIN); Annual Wormwood (GRIN); Sweet Wormwood (GRIN) 5 2, 800
Artemisia capillaris Capillary Wormwood 4 0
Artemisia dracunculus Tarragon 8 7, 717
Artemisia vulgaris Mugwort 1 168
Artocarpus altilis Breadfruit 2 6.100000001490116
Artocarpus heterophyllus Jackfruit 2 8
Asimina triloba Pawpaw 3 2.5
Aspalathus linearis Rooibos; Kaffree Tea; Red Bush Tea 4 81, 628.37999993563
Asparagus officinalis Asparagus 4 314
Astragalus membranaceus Huang-Chi; Huang Qi 4 0
Astrocaryum vulgare Awarra Palm; Tucum Palm; Tucuma Palm; Tucuma 1 2, 196, 000
Avena sativa Oats 4 382
Averrhoa bilimbi Bilimbi; Limon chino 1 28
Averrhoa carambola Carambola; Star Fruit 1 150
Azadirachta indica Neem 2 3, 000
Bactris gasipaes Peach palm; Pejibaye 2 208, 570
Ballota nigra Black Horehound 2 2, 000