An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
  1. Home
  2. COX-2-Inhibitor

COX-2-Inhibitor

Select a Results View:

Download these results as:
CSV
EXCEL
PDF
List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
PTEROSTILBENE IC50=84 uM *
PUNICIC-ACID *
QUERCETIN <40 uM *
RESVERATROL >2.5->22.5 uM *
RESVERATROL 50 uM/ *
RESVERATROL 30 uM/ Subbaramaiah, K., Michaluart, P., Chung, W. J., Dannenberg, A. J. 1998. Resveratrol Inhibits the Expression of Cyclooxygenase-2 in Human Mammary and Oral Epithelial Cells. Pharm. Biol. Suppl., 36: 35-43.
ROSMARINIC-ACID IC>58=1,000 uM *
RUTAECARPINE 2.5 ug/ml (strong activity) Kang, S. S., Kim, J. S., Son, K. H., Kim, H. P., Chang, H. W. 1999. Cyclooxygenase-2 Inhibitor from Evodia rutaecarpa. Nat. Prod. Sci., 5(2): 65-69.
SALICYLIC-ACID Newmark, T. M. and Schulick, P. 2000. Herbal Cox-2 Inhibition - Nature's Challenge to Arthritis, Cancer & Alzheimer's Disease. Hohm Press, Prescott AZ.
TRANS-RESVERATROL 20 uM/ Jang, M., Pezzuto, J. M. 1999. Cancer Chemorpreventive Activity of Resveratrol. Drugs Exp. Clin. Res., 25(2/3): 65-77.
UROLITHIN-A *
URSOLIC-ACID IC50=130 uM/ *
Download these results as:
CSV
EXCEL
PDF
List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Cichorium intybus Chicory; Witloof; Succory 5 3, 048
Cimicifuga dahurica Sheng Ma 1 0
Cimicifuga racemosa Black Cohosh; Black Snakeroot 2 48
Cinchona pubescens Quinine; Red Cinchona; Red Peruvian-Bark; Redbark 1 0
Cinchona spp Quinine 1 0
Cinnamomum aromaticum Cassia; Cassia Bark; Cassia Lignea; Chinese Cassia; Chinese Cinnamon; China Junk Cassia; Saigon Cinnamon; Zimtcassie (Ger.); Canela de la China (Sp.); Canelero chino (Sp.); Chinazimt (Ger.); Chinesischer Zimtbaum (Ger.); Kashia-Keihi (Jap.); Canelle de Cochinchine (Fr.); Cannelier Casse (Fr.); Cannelier de Chine (Fr.) 5 353, 632
Cinnamomum camphora Camphor; Ho Leaf 5 0
Cinnamomum sieboldii Japanese Cinnamon 1 0
Cinnamomum verum Cinnamon; Ceylon Cinnamon 5 9, 454, 416
Cistus ladaniferus Ambreine; Gum Cistus; Labdanum; Rockrose 1 8, 400
Citrullus colocynthis Colocynth 3 0
Citrullus lanatus Watermelon 3 3, 298
Citrus aurantiifolia Lime 1 2
Citrus aurantium Petitgrain; Bitter Orange 1 54
Citrus limon Lemon 3 37
Citrus paradisi Grapefruit 4 56
Citrus reticulata Mandarin; Tangerine 3 90.79999995231628
Citrus sinensis Orange 3 81.40000009536743
Clematis vitalba Traveler's Joy 1 0
Cnicus benedictus Blessed Thistle 6 133