Chemical URSOLIC-ACID | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

URSOLICACID

Ubiquitous

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
Analgesic	not available	Duke, 1992 *
Antialzheimeran	not available	Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Antiarrhythmic	not available	Duke, 1992 *
Antiarthritic	not available	Planta Medica, 57: A56, 1991.
Antibacterial	not available	Duke, 1992 *
Anticancer	not available	Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Anticancer (Colon)	not available	Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Anticarcinomic	not available	Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Anticariogenic	not available	Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Anticholestatic	28-100 mg/kg orl	Shukla, B., Visen, P.K.S., Patnaik, G.K., Tripathi, S.C., Srimal, R.C., Dayal, R., and Dobhal, P.C. Hepatoprotective Activity in the Rat of Ursolic Acid Isolated from Eucalyptus Hybrid. Phytotherapy Research 6: 74-79, 1992.
Anticomplement	IC100 0.1 mM/l gpg	Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Anticomplement	IC80-90 0.05 mM/l gpg	Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Antidiabetic	not available	Chemical Constituents of Oriental Herbs (3 diff. books)
AntiEBV	not available	Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antiedemic	not available	Duke, 1992 *
Antiescherichic	not available	Duke, 1992 *
Antifibrosarcomic	IC80=10 uM	Duke, 1992 *
Antihepatotoxic	5-20 mg/kg ipr	Shukla, B., Visen, P.K.S., Patnaik, G.K., Tripathi, S.C., Srimal, R.C., Dayal, R., and Dobhal, P.C. Hepatoprotective Activity in the Rat of Ursolic Acid Isolated from Eucalyptus Hybrid. Phytotherapy Research 6: 74-79, 1992.
Antihistaminic	not available	Tsuruga, T., Chun, Y.-T., Ebizuka, Y., and Sankawa, U. 1991. Biologically Active Constituents of Melaleuca leucadendron: Inhibitors of Induced Histamine Release from Rat Mast Cells. Chem. Pharm. Bull. 39(12): 3276-3278, 1991.
AntiHIV	EC50=2.0 ug/ml	Kashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Agrimonia eupatoria	Plant	not available	6000.0	-0.5	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Arbutus unedo	Leaf	not available	not available	not available	Duke, 1992 *
Arctostaphylos uva-ursi	Plant	not available	not available	not available	Duke, 1992 *
Arctostaphylos uva-ursi	Shoot	not available	not available	not available	Duke, 1992 *
Arctostaphylos uva-ursi	Leaf	4000.0	7500.0	-0.2	Duke, 1992 *
Artocarpus heterophyllus	Root	not available	not available	not available	Chemical Constituents of Oriental Herbs (3 diff. books)
Berberis vulgaris	Fruit	not available	not available	not available	Jim Duke's personal files.
Catalpa bignonioides	Leaf	not available	not available	not available	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Catharanthus roseus	Leaf	not available	not available	not available	CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses
Chimaphila umbellata	Shoot	not available	not available	not available	Duke, 1992 *
Chimaphila umbellata	Plant	not available	not available	not available	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Chrysanthemum x morifolium	Flower	not available	not available	not available	Wealth of India.
Cnicus benedictus	Plant	not available	not available	not available	Jim Duke's personal files.
Cornus florida	Plant	not available	not available	not available	Duke, 1992 *
Cornus mas	Flower	not available	not available	not available	Grigorescu, E., Ionescu, A. P. 1976. Isolation of Ursolic Acid from Cornus mas (Cornaceae). Phytochemistry, 15: 1097.
Cornus mas	Shoot	not available	not available	not available	Zorina, A. D., Matyukhina, L. G., Ryabinin, A. A. 1966. Triterpenes in Some Plant Species. Chem Nat Comp, 2(4): 291.
Cornus officinalis	Fruit	not available	not available	not available	Duke, 1992 *
Cornus officinalis	Seed	not available	not available	not available	Duke, 1992 *
Crataegus cuneata	Fruit	not available	not available	not available	Duke, 1992 *
Crataegus laevigata	Plant	not available	not available	not available	Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.