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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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COX-2-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
PTEROSTILBENE IC50=84 uM *
PUNICIC-ACID *
QUERCETIN <40 uM *
RESVERATROL 30 uM/ Subbaramaiah, K., Michaluart, P., Chung, W. J., Dannenberg, A. J. 1998. Resveratrol Inhibits the Expression of Cyclooxygenase-2 in Human Mammary and Oral Epithelial Cells. Pharm. Biol. Suppl., 36: 35-43.
RESVERATROL >2.5->22.5 uM *
RESVERATROL 50 uM/ *
ROSMARINIC-ACID IC>58=1,000 uM *
RUTAECARPINE 2.5 ug/ml (strong activity) Kang, S. S., Kim, J. S., Son, K. H., Kim, H. P., Chang, H. W. 1999. Cyclooxygenase-2 Inhibitor from Evodia rutaecarpa. Nat. Prod. Sci., 5(2): 65-69.
SALICYLIC-ACID Newmark, T. M. and Schulick, P. 2000. Herbal Cox-2 Inhibition - Nature's Challenge to Arthritis, Cancer & Alzheimer's Disease. Hohm Press, Prescott AZ.
TRANS-RESVERATROL 20 uM/ Jang, M., Pezzuto, J. M. 1999. Cancer Chemorpreventive Activity of Resveratrol. Drugs Exp. Clin. Res., 25(2/3): 65-77.
UROLITHIN-A *
URSOLIC-ACID IC50=130 uM/ *
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List of Activity Plants.
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Plant Name Common Name Chemical Count Total Parts Per Million
Canavalia ensiformis Jack Bean 1 2.400000050663948
Canna indica Achira; Queensland Arrowroot 1 0.6000000238418579
Cannabis sativa Marijuana; Marihuana; Indian Hemp; Hemp 1 0.23999999463558197
Capparis spinosa Caper; Caperbush 2 0
Capsella bursa-pastoris Shepherd's Purse 1 22
Capsicum annuum Bell Pepper; Green Pepper; Cherry Pepper; Sweet Pepper; Cone Pepper; Paprika 3 636
Capsicum frutescens Cayenne; Chili; Tabasco; Hot Pepper; Spur Pepper; Red Chili 5 798
Carica papaya Papaya 3 4, 604
Carica pentagona Babaco; Mountain papaya 1 18
Carthamus tinctorius Safflower 2 90
Carum carvi Caraway; Carum; Kummel (Ger.); Comino (Sp.); Comino de prado (Sp.) 5 15, 320
Carya illinoensis Pecan 2 0.8299999833106995
Casimiroa edulis Matasano; White sapote 1 4.800000190734863
Cassia tora Sickle Senna 1 0
Castanea sativa European Chestnut 3 0
Catalpa bignonioides Indian bean 2 0
Catha edulis Khat 1 18
Catharanthus roseus Madagascar Periwinkle; Rosy Periwinkle 4 0
Caulophyllum thalictroides Blue Cohosh 2 24
Cedrus deodora Deodar Cedar 1 0