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Biological Activity Xanthine-Oxidase-Inhibitor

List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
(+)-CATECHIN not available Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill
Livinston, Edinburgh.
(-)-EPICATECHIN IC50=>40 Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
(-)-EPIGALLOCATECHIN IC50=>40 Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
(-)-EPIGALLOCATECHIN-GALLATE IC50=>40 Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
(1'S)-1'-ACETOXYCHAVICOL-ACETATE not available Duke, 1992 *
(Z,E)-2-(3,4-DIHYDROXYPHENYL)-ETHENYL-ESTER IC50=0.021 ug/ml Chem. & Pharm. Bull. 38: 1772.
(Z,E)-2-(3,5-DIHYDROXYPHENYL)-ETHENYL-ESTER IC50=0.124 ug/ml Chem. & Pharm. Bull. 38: 1772.
1,2,3,6-TETRA-O-GALLYOL-BETA-D-GLUCOSE IC50=12 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
1,2,6-TRI-O-GALLOYL-BETA-D-GLUCOSE IC50=39 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
1,3,4,6-TETRA-O-GALLOYL-BETA-D-GLUCOSE IC50=8 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
3,5-DI-O-CAFFEOYLQUINIC-ACID IC50=34 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
3-O-GALLOYLEPICATECHINS IC50=4-7 Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
AESCULETIN IC52=10 uM Duke, 1992 *
ALLICIN 500 uM LAWSON in Koch, H. P. and Lawson, L. D., eds. 1996. Garlic- The
Science and therapeutic application of Allium sativum L. and related species. Williams & Wilkins, Baltimore. 329 pp.
ALLOPURINOL 0.021 ug/ml Duke, 1992 *
ALLOPURINOL IC50=0.17 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
APIGENIN 0.36 uM Duke, 1992 *
ASTRAGALIN-2''-GALLATE 50 uM Duke, 1992 *
ASTRAGALIN-6''-GALLATE 50 uM Duke, 1992 *
ATHYRIOL not available Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Senna alata Ringworm Bush 1 0
Senna obtusifolia Sicklepod 1 0
Senna occidentalis Coffee Senna 2 0
Serenoa repens Saw Palmetto; Scrub-Palmetto 2 261, 200
Sesamum indicum Sesame; Benneseed; Beni; Ajonjoli (Sp.); Sesamo (Sp.) 4 6.0749999433755875
Silybum marianum Milk Thistle; Lady's Thistle 3 0
Simarouba amara Simaruba Bark 1 270, 000
Skimmia arborescens Skimmia 1 0
Smilax china China Root 1 0
Solanum melongena Aubergine; Eggplant 3 4, 005.199999809265
Solanum nigrum Black Nightshade 1 100, 000
Solanum sessiliflorum Cocona 1 1, 420
Solanum torvum Susumba; Wild Eggplant 1 0
Solanum tuberosum Potato 9 33, 400.14800000191
Solidago gigantea Early Goldenrod 3 21, 980
Solidago virgaurea European Goldenrod; Woundwort 2 0
Sophora japonica Japanese Pagoda Tree 2 0
Sorbus aucubaria Rowan Berry 5 0
Spartium junceum Genet; Spanish Broom; Weaver's Broom 3 0
Spigelia marilandica Indian Pink; Pinkroot 1 0