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Biological Activity Xanthine-Oxidase-Inhibitor

List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
(+)-CATECHIN not available Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill
Livinston, Edinburgh.
(-)-EPICATECHIN IC50=>40 Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
(-)-EPIGALLOCATECHIN IC50=>40 Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
(-)-EPIGALLOCATECHIN-GALLATE IC50=>40 Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
(1'S)-1'-ACETOXYCHAVICOL-ACETATE not available Duke, 1992 *
(Z,E)-2-(3,4-DIHYDROXYPHENYL)-ETHENYL-ESTER IC50=0.021 ug/ml Chem. & Pharm. Bull. 38: 1772.
(Z,E)-2-(3,5-DIHYDROXYPHENYL)-ETHENYL-ESTER IC50=0.124 ug/ml Chem. & Pharm. Bull. 38: 1772.
1,2,3,6-TETRA-O-GALLYOL-BETA-D-GLUCOSE IC50=12 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
1,2,6-TRI-O-GALLOYL-BETA-D-GLUCOSE IC50=39 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
1,3,4,6-TETRA-O-GALLOYL-BETA-D-GLUCOSE IC50=8 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
3,5-DI-O-CAFFEOYLQUINIC-ACID IC50=34 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
3-O-GALLOYLEPICATECHINS IC50=4-7 Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
AESCULETIN IC52=10 uM Duke, 1992 *
ALLICIN 500 uM LAWSON in Koch, H. P. and Lawson, L. D., eds. 1996. Garlic- The
Science and therapeutic application of Allium sativum L. and related species. Williams & Wilkins, Baltimore. 329 pp.
ALLOPURINOL 0.021 ug/ml Duke, 1992 *
ALLOPURINOL IC50=0.17 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
APIGENIN 0.36 uM Duke, 1992 *
ASTRAGALIN-2''-GALLATE 50 uM Duke, 1992 *
ASTRAGALIN-6''-GALLATE 50 uM Duke, 1992 *
ATHYRIOL not available Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Rumex crispus Curly Dock; Lengua De Vaca; Yellow Dock; Sour Dock 5 240, 000
Rumex hymenosepalus Canaigre 1 350, 000
Ruta graveolens Rue 2 0
Salix alba White Willow 5 120, 000
Salvia officinalis Sage 8 80, 000
Salvia sclarea Clary Sage 1 0
Salvia sp. Chia 1 306
Sambucus canadensis American Elder; Elderberry; American Elderberry; Sweet Elder 2 0
Sambucus nigra European Alder; European Elder; European Elderberry; Elder; Black Elder 4 150, 000
Sambucus simpsonii Simpson's elderberry 1 0
Sanguisorba minor Small Burnet 4 0
Sanguisorba officinalis Greater Burnet 3 340, 000
Santalum album White Sandalwood 1 0
Santolina chamaecyparissus Lavender Cotton 5 0
Sarcostemma acidum Soma 1 0
Sarracenia alata not available 1 0
Sarracenia flava not available 1 0
Sarracenia leucophylla not available 1 0
Sarracenia minor not available 1 0
Sarracenia oreophila not available 1 0