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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Xanthine-Oxidase-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
(+)-CATECHIN Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill
Livinston, Edinburgh.
(-)-EPICATECHIN IC50=>40 Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
(-)-EPIGALLOCATECHIN IC50=>40 Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
(-)-EPIGALLOCATECHIN-GALLATE IC50=>40 Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
(1'S)-1'-ACETOXYCHAVICOL-ACETATE *
(Z,E)-2-(3,4-DIHYDROXYPHENYL)-ETHENYL-ESTER IC50=0.021 ug/ml Chem. & Pharm. Bull. 38: 1772.
(Z,E)-2-(3,5-DIHYDROXYPHENYL)-ETHENYL-ESTER IC50=0.124 ug/ml Chem. & Pharm. Bull. 38: 1772.
1,2,3,6-TETRA-O-GALLYOL-BETA-D-GLUCOSE IC50=12 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
1,2,6-TRI-O-GALLOYL-BETA-D-GLUCOSE IC50=39 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
1,3,4,6-TETRA-O-GALLOYL-BETA-D-GLUCOSE IC50=8 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
3,5-DI-O-CAFFEOYLQUINIC-ACID IC50=34 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
3-O-GALLOYLEPICATECHINS IC50=4-7 Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
AESCULETIN IC52=10 uM *
ALLICIN 500 uM LAWSON in Koch, H. P. and Lawson, L. D., eds. 1996. Garlic- The
Science and therapeutic application of Allium sativum L. and related species. Williams & Wilkins, Baltimore. 329 pp.
ALLOPURINOL 0.021 ug/ml *
ALLOPURINOL IC50=0.17 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
APIGENIN 0.36 uM *
ASTRAGALIN-2''-GALLATE 50 uM *
ASTRAGALIN-6''-GALLATE 50 uM *
ATHYRIOL Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Spinacia oleracea Spinach 5 99.1299991607666
Spondias pinnata Yellow Mombin; Yellow Plum 1 0
Stachys officinalis Betony; Wood Betony; Bishop's-Wort; Purple Betony 3 620, 000
Stellaria media Chickweed; Common Chickweed 3 0
Sterculia urens Karaya 1 20, 000
Stillingia sylvatica Queen's-Delight; Stillingia; Queen's-Root; Yawroot 1 0
Swertia chirata Chirata; Chiretta 1 0
Symphytum officinale Comfrey 2 90, 000
Symplocarpus foetidus Skunk Cabbage 1 0
Syzygium aromaticum Clove; Clovetree 14 31, 573.800003051758
Syzygium cumini Aceituna Dulce; Jambolan; Java Plum 3 0.5400000214576721
Tabebuia impetiginosa Pau d'arco; Taheebo 1 0
Tabernanthe iboga Iboga 1 0
Tagetes lucida Sweet-Mace; Sweet-Scent Marigold; Sweet-Scent Mexican Marigold; Anise Marigold 1 0
Tagetes minuta Wild Marigold; Aztec Marigold; Dwarf Marigold; Mexican Marigold; Muster John Henry; Stinking-Roger 1 0
Tagetes patula French Marigold 3 0
Tamarindus indica Tamarind; Kilytree; Indian Tamarind 2 420, 000
Tanacetum vulgare Tansy 3 0
Taraxacum officinale Dandelion 5 0
Taxus baccata Common Yew 2 4.999999821186066