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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Xanthine-Oxidase-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
NEPETIN *
OENOTHEIN-B IC50=20 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
OENOTHEIN-C IC50=11 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
OPC IC50=>40 Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
OPCS IC50=>40 Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
OSTHOL IC10=10 uM *
PEDUNCULAGIN IC50=18 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
PENTA-O-GALLOYL-BETA-D-GLUCOSE IC50=3.3 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
POLYPHENOLS *
PROCYANIDIN IC50=>40 Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
PROCYANIDINS IC50=>40 Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
PROCYANIDINS IC50=2.4 uM/l *
PUERARIN Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill
Livinston, Edinburgh.
QUERCETIN 3.1 uM *
QUERCETIN IC50=>0.4 ug/ml Chem. & Pharm. Bull. 38: 1772.
QUERCETIN IC50=10.6 ug/ml *
RABDOSIN IC50=>40 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
RUGOSIN-A IC50=8 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
RUGOSIN-D IC50=3.1 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
TANNIN *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Senna alata Ringworm Bush 1 0
Senna obtusifolia Sicklepod 1 0
Senna occidentalis Coffee Senna 2 0
Serenoa repens Saw Palmetto; Scrub-Palmetto 2 261, 200
Sesamum indicum Sesame; Benneseed; Beni; Ajonjoli (Sp.); Sesamo (Sp.) 4 6.0749999433755875
Silybum marianum Milk Thistle; Lady's Thistle 3 0
Simarouba amara Simaruba Bark 1 270, 000
Skimmia arborescens Skimmia 1 0
Smilax china China Root 1 0
Solanum melongena Aubergine; Eggplant 3 4, 005.199999809265
Solanum nigrum Black Nightshade 1 100, 000
Solanum sessiliflorum Cocona 1 1, 420
Solanum torvum Susumba; Wild Eggplant 1 0
Solanum tuberosum Potato 9 33, 400.14800000191
Solidago gigantea Early Goldenrod 3 21, 980
Solidago virgaurea European Goldenrod; Woundwort 2 0
Sophora japonica Japanese Pagoda Tree 2 0
Sorbus aucubaria Rowan Berry 5 0
Spartium junceum Genet; Spanish Broom; Weaver's Broom 3 0
Spigelia marilandica Indian Pink; Pinkroot 1 0