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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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COX-1-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
MYRICETIN-3-O-BETA-D-GLUCURONIDE IC50=10 uM/ Hiermann, A., Schramm, H. W., Laufer, S. 1998. Anti-Inflammatory Activity of Myricetin-3--O-beta-d-glucuronide and Related Compounds. Inflamm. Res., 47(11): 421-427.
N-2'-METHYL-BUTYL-DECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml (weak activity) Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-DODECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml (weak activity) Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-HEXADECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml (weak activity) Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-OCTA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-OCTADECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-TETRADECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
PELLITORINE IC50 @ ug/ml Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
PINOSTROBIN IC36=100 ug/ml *
PTEROSTILBENE IC50=20 uM *
PUNICIC-ACID *
RESVERATROL ED50=15 uM *
RESVERATROL 50 uM/ Jang, M. S., Pezzuto, J. M. 1998. Resveratrol Blocks Eicosanoid Production and Chemically-Induced Cellular Transformation: Implication for Cancer Chemoprevention. Pharm Biol Suppl, 36: 28-34.
ROSMARINIC-ACID IC58=1,000 uM *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Solanum nigrum Black Nightshade 1 110
Solanum quitoensis Naranjillo 1 16
Solanum sessiliflorum Cocona 1 14
Solanum torvum Susumba; Wild Eggplant 1 54
Solanum tuberosum Potato 2 143.00999999977648
Sonchus oleraceus Cerraja; Sow Thistle 1 1, 090
Sorbus aucubaria Rowan Berry 1 98
Spinacia oleracea Spinach 1 722.5
Spirulina pratensis Spirulina 1 478
Spirulina spp. Spirulina 1 480
Spondias dulcis Ambarella 1 16
Spondias mombin Yellow Mombin; Yellow Plum 1 230
Spondias pinnata Yellow Mombin; Yellow Plum 1 56
Spondias purpurea Purple Jobo; Purple Plum 1 18
Stachys officinalis Betony; Wood Betony; Bishop's-Wort; Purple Betony 3 0
Stellaria media Chickweed; Common Chickweed 3 86
Stevia rebaudiana Ca-A-E; Sweet Leaf of Paraguay; Stevia 2 225
Symphytum officinale Comfrey 2 5, 768
Syzygium aromaticum Clove; Clovetree 2 1, 780, 806
Syzygium cumini Aceituna Dulce; Jambolan; Java Plum 1 9