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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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COX-1-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
MYRICETIN-3-O-BETA-D-GLUCURONIDE IC50=10 uM/ Hiermann, A., Schramm, H. W., Laufer, S. 1998. Anti-Inflammatory Activity of Myricetin-3--O-beta-d-glucuronide and Related Compounds. Inflamm. Res., 47(11): 421-427.
N-2'-METHYL-BUTYL-DECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml (weak activity) Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-DODECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml (weak activity) Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-HEXADECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml (weak activity) Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-OCTA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-OCTADECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-TETRADECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
PELLITORINE IC50 @ ug/ml Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
PINOSTROBIN IC36=100 ug/ml *
PTEROSTILBENE IC50=20 uM *
PUNICIC-ACID *
RESVERATROL ED50=15 uM *
RESVERATROL 50 uM/ Jang, M. S., Pezzuto, J. M. 1998. Resveratrol Blocks Eicosanoid Production and Chemically-Induced Cellular Transformation: Implication for Cancer Chemoprevention. Pharm Biol Suppl, 36: 28-34.
ROSMARINIC-ACID IC58=1,000 uM *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Syzygium jambos Pomarrosa; Rose Apple 1 17
Syzygium malaccense Malay Apple; Mammey Pomorrosa; Ohia 1 0.23999999463558197
Tabebuia heptaphylla Pau D'Arco 1 4.300000190734863
Tagetes erecta Marigold; Aztec Marigold 1 0
Tamarindus indica Tamarind; Kilytree; Indian Tamarind 2 363
Tanacetum parthenium Feverfew 2 1, 014
Tanacetum vulgare Tansy 1 0
Taraxacum officinale Dandelion 2 667
Taxus baccata Common Yew 1 0
Tecoma stans Yellow Elder 1 0
Terminalia arjuna Arjun; Arjuna 1 16.600000381469727
Terminalia catappa Indian Almond; Tropical Almond; Malabar Almond 2 5.3999998569488525
Terminalia pallida 1 1, 000
Tetragonia tetragonioides New Zealand Spinach 1 440
Teucrium polium Golden Germander 2 0
Teucrium scorodonia Germander; Wood Germander 1 0
Theobroma bicolor Nicaraguan Cacao; Pataste 1 18
Theobroma cacao Cacao 2 4, 000
Thuja occidentalis Arbor-Vitae; Northern White-Cedar 1 0
Thymus capitatus 'Sicilian' Thyme; Spanish Origanum; Spanish Thyme 1 63