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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Lipoxygenase-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
POLYPHENOLS *
PROCYANIDIN-D2 IC29=1.25 mM Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
QUERCETIN IC11=1.25 mM Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
QUERCETIN IC50=0.1-5 uM *
ROSMARINIC-ACID *
RUTIN IC75=2.5 mM Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
SCANDENOLIDE IC50=30-60uM *
SQUALENE Chemical Express, 7: 297, 1992.
TANNIN *
TAXIFOLIN Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
THEAFLAVIN IC50=3,604 uM Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
THEAFLAVIN-DIGALLATE IC50=0.25 uM Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
THEAFLAVIN-MONOGALLATE-B IC50=0.62 uM Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
THYMOQUINONE IC50 1 ug/ml Houghton, P.J., Zarka, R., Heras, B., and Hoult, J.R.S. 1994. Fixed Oil of Nigella sativa and Derived Thymoquinone Inhibit Eicosanoid Generation in Leukocytes and Membrane Lipid Peroxidation. Planta Medica, 61: 33.
TOCOPHEROL Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
UMBELLIFERONE *
URSOLIC-ACID IC50=0.18 mM *
URUSHIOL Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
UVAOL *
VERBASCOSIDE Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
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List of Activity Plants.
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Plant Name Common Name Chemical Count Total Parts Per Million
Aloe vera Bitter Aloes; Aloe 3 0
Aloysia citrodora Lemon Verbena 3 0
Alpinia galanga Greater Galangal; Siamese Ginger; Languas 1 0
Alpinia officinarum Lesser Galangal; Chinese Ginger 4 2, 000
Althaea officinalis Marshmallow; White Mallow 9 40, 000
Amaranthus sp. Pigweed 1 0
Amaranthus spinosus Spiny pigweed 1 0
Ammi majus Bishop's Weed 4 4, 500
Ammi visnaga Visnaga 6 0
Anacardium occidentale Cashew 4 90, 008
Ananas comosus Pineapple 2 730
Anaphalis margaritacea Pearly Everlasting 1 0
Anastatica hierochuntica Jericho Rose 2 0
Andira inermis Cabbage Bark 1 0
Anemone pulsatilla Pasque Flower 3 0
Anethum graveolens Dill; Garden Dill 11 7, 392
Angelica archangelica Garden Angelica; Angelica; Wild Parsnip 3 600
Angelica sinensis Dang Gui; Dong Quai; Dang Quai; Dang Qui; Dong Gui; Chinese Angelica 2 462
Anisochilus carnosus Panjiri-ka Pat 1 0
Annona muricata Soursop 3 0