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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Lipoxygenase-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
POLYPHENOLS *
PROCYANIDIN-D2 IC29=1.25 mM Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
QUERCETIN IC11=1.25 mM Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
QUERCETIN IC50=0.1-5 uM *
ROSMARINIC-ACID *
RUTIN IC75=2.5 mM Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
SCANDENOLIDE IC50=30-60uM *
SQUALENE Chemical Express, 7: 297, 1992.
TANNIN *
TAXIFOLIN Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
THEAFLAVIN IC50=3,604 uM Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
THEAFLAVIN-DIGALLATE IC50=0.25 uM Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
THEAFLAVIN-MONOGALLATE-B IC50=0.62 uM Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
THYMOQUINONE IC50 1 ug/ml Houghton, P.J., Zarka, R., Heras, B., and Hoult, J.R.S. 1994. Fixed Oil of Nigella sativa and Derived Thymoquinone Inhibit Eicosanoid Generation in Leukocytes and Membrane Lipid Peroxidation. Planta Medica, 61: 33.
TOCOPHEROL Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
UMBELLIFERONE *
URSOLIC-ACID IC50=0.18 mM *
URUSHIOL Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
UVAOL *
VERBASCOSIDE Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
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List of Activity Plants.
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Plant Name Common Name Chemical Count Total Parts Per Million
Viburnum prunifolium Black Haw 6 20, 000
Vicia faba Broadbean; Faba Bean; Habas 5 0
Vigna radiata Green Gram; Mungbean 4 0
Vinca minor Periwinkle; Running-Myrtle 3 100, 800
Viola odorata Common Violet; Sweet Violet 3 40, 000
Viola tricolor Pansy; Wild Violet 6 460, 604
Viscum album European Mistletoe 1 0
Vitex agnus-castus Chaste-Tree 2 0
Vitis vinifera Grape; European Grape; Wine Grape; Grapevine; Vigne Vinifere (Fr.); Weinrebe (Ger.); Parra (Sp.); Vid (Sp.) 17 11, 546.400001525879
Warburgia ugandensis Warburghia 1 0
Withania somnifera Ashwagandha 3 0
Xanthorhiza simplicissima Yellowroot 2 13, 000
Xylopia aethiopica Ethiopian Pepper; Guinea Pepper; Negro Pepper; Spice Tree; Mohrenpfeffer (Ger.); Maniguete (Sp.); Pimienta de Guinea (Sp.) 1 0
Yucca baccata Spanish Bayonet; Yucca; Banana Yucca; Blue Yucca 1 0
Zanthoxylum alatum Indian Prickly Ash; Wartara Oil Tree 1 0
Zanthoxylum americanum Northern Prickly Ash 3 0
Zanthoxylum clava-herculis Pepperbark; Southern Prickly Ash; Hercules'-Club; West Indian Yellowwood 1 0
Zea mays Corn 5 48.39999997615814
Zingiber officinale Ginger 6 19
Zizyphus jujuba Da-Zao; Jujube; Ta-Tsao 3 483, 000