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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Lipoxygenase-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
POLYPHENOLS *
PROCYANIDIN-D2 IC29=1.25 mM Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
QUERCETIN IC11=1.25 mM Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
QUERCETIN IC50=0.1-5 uM *
ROSMARINIC-ACID *
RUTIN IC75=2.5 mM Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
SCANDENOLIDE IC50=30-60uM *
SQUALENE Chemical Express, 7: 297, 1992.
TANNIN *
TAXIFOLIN Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
THEAFLAVIN IC50=3,604 uM Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
THEAFLAVIN-DIGALLATE IC50=0.25 uM Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
THEAFLAVIN-MONOGALLATE-B IC50=0.62 uM Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
THYMOQUINONE IC50 1 ug/ml Houghton, P.J., Zarka, R., Heras, B., and Hoult, J.R.S. 1994. Fixed Oil of Nigella sativa and Derived Thymoquinone Inhibit Eicosanoid Generation in Leukocytes and Membrane Lipid Peroxidation. Planta Medica, 61: 33.
TOCOPHEROL Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
UMBELLIFERONE *
URSOLIC-ACID IC50=0.18 mM *
URUSHIOL Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
UVAOL *
VERBASCOSIDE Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
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List of Activity Plants.
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Plant Name Common Name Chemical Count Total Parts Per Million
Annona reticulata Custard Apple 1 0
Annona squamosa Sugar-Apple; Sweetsop 1 0
Anogeissus latifolia Gum Ghatti 3 479, 000
Apium graveolens Celery 9 2, 320
Apocynum cannabinum Bitterroot; Spreading Dogbane 1 0
Arachis hypogaea Groundnut; Peanut 6 108
Araucaria bidwillii Monkey puzzle 4 10, 000
Arbutus unedo Arbutus; Strawberry Tree 3 1, 220, 000
Arctium lappa Gobo; Great Burdock; Burdock 3 124, 500
Arctostaphylos uva-ursi Bearberry; Uva Ursi 8 555, 000
Ardisia japonica Marlberry 1 0
Areca catechu Betel Nut; Pin-Lang 1 500, 000
Argemone mexicana Prickly Poppy 2 11, 410
Armoracia rusticana Horseradish 5 6
Arnica montana Leopard's-Bane; Mountain Tobacco 3 0
Artemisia abrotanum Southernwood 5 0
Artemisia absinthium Wormwood 4 77, 000
Artemisia annua Qinghao; Sweet Annie; Annual Mugwort (GRIN); Annual Wormwood (GRIN); Sweet Wormwood (GRIN) 4 0
Artemisia capillaris Capillary Wormwood 2 0
Artemisia cina Levant Wormseed 1 0