Biological Activity Lipoxygenase-Inhibitor | Dr. Duke's Phytochemical and Ethnobotanical Databases

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name	Dosage	Reference
POLYPHENOLS	not available	Duke, 1992 *
PROCYANIDIN-D2	IC29=1.25 mM	Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
QUERCETIN	IC11=1.25 mM	Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
QUERCETIN	IC50=0.1-5 uM	Duke, 1992 *
ROSMARINIC-ACID	not available	Duke, 1992 *
RUTIN	IC75=2.5 mM	Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
SCANDENOLIDE	IC50=30-60uM	Duke, 1992 *
SQUALENE	not available	Chemical Express, 7: 297, 1992.
TANNIN	not available	Duke, 1992 *
TAXIFOLIN	not available	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
THEAFLAVIN	IC50=3,604 uM	Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
THEAFLAVIN-DIGALLATE	IC50=0.25 uM	Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
THEAFLAVIN-MONOGALLATE-B	IC50=0.62 uM	Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
THYMOQUINONE	IC50 1 ug/ml	Houghton, P.J., Zarka, R., Heras, B., and Hoult, J.R.S. 1994. Fixed Oil of Nigella sativa and Derived Thymoquinone Inhibit Eicosanoid Generation in Leukocytes and Membrane Lipid Peroxidation. Planta Medica, 61: 33.
TOCOPHEROL	not available	Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
UMBELLIFERONE	not available	Duke, 1992 *
URSOLIC-ACID	IC50=0.18 mM	Duke, 1992 *
URUSHIOL	not available	Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
UVAOL	not available	Duke, 1992 *
VERBASCOSIDE	not available	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.

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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name	Common Name	Chemical Count	Total Parts Per Million
Citrullus lanatus	Watermelon	2	16, 500
Citrus aurantium	Petitgrain; Bitter Orange	4	5, 000
Citrus limon	Lemon	8	68, 979
Citrus medica	Citron	1	0
Citrus paradisi	Grapefruit	8	180
Citrus reticulata	Mandarin; Tangerine	3	95, 600
Citrus sinensis	Orange	7	78, 909.30000019073
Citrus spp	Citrus	1	0
Clematis vitalba	Traveler's Joy	2	0
Cnicus benedictus	Blessed Thistle	6	80, 000
Coccinia grandis	Ivy Gourd; Kundree; Tindora; Tindori; Pepasan; Little Gourd; Kanduri	1	0
Cocos nucifera	Coconut; Coconut Palm; Copra; Nariyal; Kokospalme (Ger.); Cocotero (Sp.)	3	0
Coffea arabica	Coffee	5	170, 000
Cola acuminata	Abata Cola	3	0
Coleus barbatus	Forskohl's Coleus	1	85.80000305175781
Collinsonia canadensis	Stone Root	2	0
Commelina communis	Common dayflower	1	0
Commiphora myrrha	Myrrh; African Myrrh; Herabol Myrrh; Somali Myrrh; Myrrhe (Fr., Ger.); Mirra (Sp. It.)	1	0
Commiphora wightii	Guggul; Indian Bdellium-Tree	1	0
Conium maculatum	Poison Hemlock; Hemlock; Spotted Hemlock; Fool's Parsley; Carrot Fern; Spotted Parsley	3	240, 000