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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antiplasmodial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
EURYCOMANONE IC50=1.2-4.9 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
EXIGUAFLAVANONE-A IC50=4.6-7.1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
EXIGUAFLAVONE-A EC50=4.6 ug/ml Chanphen, R., Thebtaranonth, Y., Wanauppathamkul, S., and Yuthavong, Y. 1998. Antimalarial Principles from Artemisia indica. J. Nat. Prod., 61 (9):1146-1147.
EXIGUAFLAVONE-B EC50=7 ug/ml Chanphen, R., Thebtaranonth, Y., Wanauppathamkul, S., and Yuthavong, Y. 1998. Antimalarial Principles from Artemisia indica. J. Nat. Prod., 61 (9):1146-1147.
FAGARAMIDE IC50=12.3 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
FAGARONINE IC50=0.009 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
FEBRIFUGINE IC50=0.001-0.07 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
GALIPININE IC50=0.9 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
GLAUCARUBINONE 6 ug/ml Grenand, P., Moretti, C., and Jacquemin, H. 1987. Pharmacopees Traditionnelles en Guyane. l'ORSTROM, Paris. 569 pp.
GLINOSIDE-A IC50=30-42 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
GOSSYPOL IC50=10 uM *
GUTOLACTONE IC50=0.004 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
HEPTAPHYLLINE IC50=3-6 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
HEXAMETHOXYLIGNAN IC50=37-50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
HUMULENE IC50=86 ug/ml *
HYDRANTHINE-A IC50=0.1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
HYDROXYCRYPTOLEPINE IC50=77-102 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ICAJINE IC50=>80-95 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOCHONDRODENDRINE IC50=892 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOCRYPTOLEPINE IC50=0.8 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Cuphea infundibulum 1 22.299999237060547
Curcuma longa Turmeric; Indian Saffron 1 190
Cyamopsis tetragonoloba Guar; Cluster-Bean; Siam-Bean 2 0
Cymbopogon citratus West Indian Lemongrass; Lemongrass 1 0
Cynara cardunculus Artichoke 2 0
Cyperus rotundus Nutsedge 4 5, 000
Cytisus scoparius Scotch Broom 1 0
Daemonorops draco Dragon's Blood 1 0
Datura innoxia Thorn Apple 1 0
Daucus carota Carrot 2 410
Dendroseris neriifolia 1 0
Dichrostachys glomerata 1 35
Dicoma tomentosa 1 0
Digitalis purpurea Purple Foxglove 1 0
Dillenia anhamanica 1 5, 000
Dillenia aurea 1 7, 200
Dillenia bracteata 1 5, 800
Dillenia indica 1 49, 900
Dillenia pentagyna 1 9, 800
Dillenia retusa 1 35, 400