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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antiplasmodial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
EURYCOMANONE IC50=1.2-4.9 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
EXIGUAFLAVANONE-A IC50=4.6-7.1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
EXIGUAFLAVONE-A EC50=4.6 ug/ml Chanphen, R., Thebtaranonth, Y., Wanauppathamkul, S., and Yuthavong, Y. 1998. Antimalarial Principles from Artemisia indica. J. Nat. Prod., 61 (9):1146-1147.
EXIGUAFLAVONE-B EC50=7 ug/ml Chanphen, R., Thebtaranonth, Y., Wanauppathamkul, S., and Yuthavong, Y. 1998. Antimalarial Principles from Artemisia indica. J. Nat. Prod., 61 (9):1146-1147.
FAGARAMIDE IC50=12.3 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
FAGARONINE IC50=0.009 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
FEBRIFUGINE IC50=0.001-0.07 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
GALIPININE IC50=0.9 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
GLAUCARUBINONE 6 ug/ml Grenand, P., Moretti, C., and Jacquemin, H. 1987. Pharmacopees Traditionnelles en Guyane. l'ORSTROM, Paris. 569 pp.
GLINOSIDE-A IC50=30-42 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
GOSSYPOL IC50=10 uM *
GUTOLACTONE IC50=0.004 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
HEPTAPHYLLINE IC50=3-6 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
HEXAMETHOXYLIGNAN IC50=37-50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
HUMULENE IC50=86 ug/ml *
HYDRANTHINE-A IC50=0.1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
HYDROXYCRYPTOLEPINE IC50=77-102 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ICAJINE IC50=>80-95 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOCHONDRODENDRINE IC50=892 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOCRYPTOLEPINE IC50=0.8 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Centaurea cyanus Cornflower; Bachelor's Button 1 0
Centaurium erythraea Centaury 1 0
Centella asiatica Gotu Kola; Pennywort 2 2, 200
Cephaelis ipecacuanha Ipecac; Raicilla 2 35, 400
Ceratonia siliqua Carob; St.John's-Bread; Locust Bean 1 0
Chamaecrista greggii 1 14.800000190734863
Chamaemelum nobile Garden Camomile; Perennial Camomile; Roman Camomile 4 0
Chelidonium majus Celandine 1 0
Chenopodium album Lambsquarter 1 0
Chenopodium quinoa 1 0
Chimaphila umbellata King's Cure; Pipsissewa 2 0
Chrysanthemum x morifolium Chrysanthemum; Florist's Chrysanthemum; Mum; Ju Hua (Pinyin) 2 480
Cichorium endivia Endive; Escarole 1 0
Cichorium intybus Chicory; Witloof; Succory 1 3
Cinnamomum aromaticum Cassia; Cassia Bark; Cassia Lignea; Chinese Cassia; Chinese Cinnamon; China Junk Cassia; Saigon Cinnamon; Zimtcassie (Ger.); Canela de la China (Sp.); Canelero chino (Sp.); Chinazimt (Ger.); Chinesischer Zimtbaum (Ger.); Kashia-Keihi (Jap.); Canelle de Cochinchine (Fr.); Cannelier Casse (Fr.); Cannelier de Chine (Fr.) 2 0
Cinnamomum camphora Camphor; Ho Leaf 3 0
Cinnamomum verum Cinnamon; Ceylon Cinnamon 2 266.79999923706055
Citrullus colocynthis Colocynth 1 0
Citrus limon Lemon 1 0
Citrus mitis Calamansi; Calamondin 1 0