Chemical OLEANOLIC-ACID | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

OLEANOLICACID

Ubiquitous

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
Antiviral	IC50=21.8 ug/ml	Kashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
Aromatase-Inhibitor	not available	Duke, 1992 *
Beta-Blocker	not available	Duke, 1992 *
Beta-Glucuronidase-Inhibitor	~100 mg/kg	Duke, 1992 *
Cancer-Preventive	not available	Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardioprotective	40 mg/kg	Duke, 1992 *
Cardiotonic	not available	Duke, 1992 *
COX-2-Inhibitor	IC50=295 uM/	Duke, 1992 *
COX-2-Inhibitor	not available	Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Cyclooxygenase-Inhibitor	not available	Duke, 1992 *
Diuretic	not available	Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Elastase-Inhibitor	IC50=~15 uM	Duke, 1992 *
Hepatoprotective	not available	Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 211.
Hypolipemic	not available	Duke, 1992 *
Hypotensive	not available	Duke, 1992 *
Immunomodulator	not available	Duke, 1992 *
Leucocytogenic	not available	Duke, 1992 *
NF-kB-Inhibitor	not available	Duke, 1992 *
Phagocytotic	not available	Duke, 1992 *
Piscicide	not available	ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Melissa officinalis	Shoot	not available	not available	not available	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Mentha spicata	Leaf	not available	not available	not available	Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
Mentha spicata	Shoot	not available	not available	not available	Duke, 1992 *
Mentha x rotundifolia	Tissue Culture	not available	not available	not available	Jim Duke's personal files.
Myristica fragrans	Seed	not available	not available	not available	Chemical Constituents of Oriental Herbs (3 diff. books)
Myroxylon balsamum	Plant	not available	not available	not available	Duke, 1992 *
Nerium oleander	Plant	not available	not available	not available	Duke, 1992 *
Ocimum basilicum	Flower	not available	1300.0	-0.6	Duke, 1992 *
Ocimum basilicum	Leaf	not available	1700.0	0.2	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Ocimum suave	Leaf	not available	not available	not available	J. Nat. Prod. 44: 308.
Ocimum tenuiflorum	Leaf	0.0	2180.0	0.5	Duke, 1992 *
Olea europaea	Petiole	not available	not available	not available	Duke, 1992 *
Olea europaea	Hull Husk	not available	not available	not available	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Origanum majorana	Plant	not available	4700.0	0.2	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Origanum vulgare	Plant	not available	not available	not available	Duke, 1992 *
Panax ginseng	Root	150.0	700.0	0.8	Duke, 1992 *
Panax japonicus	Rhizome	not available	not available	not available	Duke, 1992 *
Panax quinquefolius	Root	600.0	980.0	1.5	Duke, 1992 *
Panax quinquefolius	Plant	not available	20.0	-1.2	Duke, 1992 *
Phoradendron juniperinum	Shoot	not available	3.0	-1.4	Kashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.