Chemical OLEANOLIC-ACID | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

OLEANOLICACID

Ubiquitous

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
Antimalarial	IC50=70-89 ug/ml	Duke, 1992 *
Antinephritic	IC50=19-24 uM	Duke, 1992 *
Antioxidant	not available	Balanehru, S. and Nagarajan, B. 1992. Intervention of Adriamycin Induced Free Radical Damage. Biochemistry International 28(4): 735-744, 1992.
Antioxidant	IC46=10 uM	Duke, 1992 *
Antiperiodontic	MIC=625-1,250 ug/ml	Duke, 1992 *
Antiperoxidant	IC30=200 ug/ml	Duke, 1992 *
AntiPGE2	IC50=24 uM	Duke, 1992 *
Antiplaque	MIC=625-1,250 ug/ml	Duke, 1992 *
Antiplasmodial	IC50=70-89 ug/ml	Duke, 1992 *
Antisarcomic	not available	Duke, 1992 *
Antiseptic	MIC=625-1,250 ug/ml	Duke, 1992 *
AntiTGF-beta	IC50=19-24 uM	Duke, 1992 *
Antitumor	not available	Duke, 1992 *
Antitumor (Breast)	not available	Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Colon)	not available	Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Kidney)	not available	Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Lung)	not available	Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Pancreas)	not available	Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antiulcer	>carbenoxolone	Duke, 1992 *
Antiviral	IC50=21.8 ug/ml	Kashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Melissa officinalis	Shoot	not available	not available	not available	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Mentha spicata	Leaf	not available	not available	not available	Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
Mentha spicata	Shoot	not available	not available	not available	Duke, 1992 *
Mentha x rotundifolia	Tissue Culture	not available	not available	not available	Jim Duke's personal files.
Myristica fragrans	Seed	not available	not available	not available	Chemical Constituents of Oriental Herbs (3 diff. books)
Myroxylon balsamum	Plant	not available	not available	not available	Duke, 1992 *
Nerium oleander	Plant	not available	not available	not available	Duke, 1992 *
Ocimum basilicum	Flower	not available	1300.0	-0.6	Duke, 1992 *
Ocimum basilicum	Leaf	not available	1700.0	0.2	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Ocimum suave	Leaf	not available	not available	not available	J. Nat. Prod. 44: 308.
Ocimum tenuiflorum	Leaf	0.0	2180.0	0.5	Duke, 1992 *
Olea europaea	Hull Husk	not available	not available	not available	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Olea europaea	Petiole	not available	not available	not available	Duke, 1992 *
Origanum majorana	Plant	not available	4700.0	0.2	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Origanum vulgare	Plant	not available	not available	not available	Duke, 1992 *
Panax ginseng	Root	150.0	700.0	0.8	Duke, 1992 *
Panax japonicus	Rhizome	not available	not available	not available	Duke, 1992 *
Panax quinquefolius	Root	600.0	980.0	1.5	Duke, 1992 *
Panax quinquefolius	Plant	not available	20.0	-1.2	Duke, 1992 *
Phoradendron juniperinum	Shoot	not available	3.0	-1.4	Kashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.