Chemical OLEANOLIC-ACID | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

OLEANOLICACID

Ubiquitous

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Sort descending	Dosage	Reference
Abortifacient	not available	Duke, 1992 *
Antiallergic	not available	Duke, 1992 *
Antiarrhythmic	40 mg/kg	Duke, 1992 *
Antiatherosclerotic	not available	Duke, 1992 *
Antibacterial	MIC=625-1,250 ug/ml	Duke, 1992 *
Anticarcinomic	not available	Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Anticariogenic	not available	Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Anticomplement	IC40-50 0.01 mM/l gpg	Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Anticomplement	IC80-90 0.05 mM/l gpg	Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Antiedemic	IC36=40 mg/kg ipr rat	Duke, 1992 *
Antifertility	not available	Duke, 1992 *
Antigingivitic	MIC=625-1,250 ug/ml	Duke, 1992 *
Antihepatotoxic	not available	Duke, 1992 *
AntiHIV	IC50=21.8 ug/ml	Duke, 1992 *
AntiHIV	EC50=1.7 ug/ml	Kashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
Antihyperlipidemic	not available	Duke, 1992 *
Antiinflammatory	40 mg/kg ipr	Aquino, R., De Feo, V., De Simone, F., Pizza, C.*, and Cirino, G. Plant Metabolites. New Compounds And Anti-Inflammatory Activity Of Uncaria tomentosa. Journal of Natural Products, 54(2): 453-459, 1991.
Antiischemic	40 mg/kg	Duke, 1992 *
Antileukemic	not available	Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antileukotriene	IC50=17 uM	Duke, 1992 *

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name Sort descending	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Melissa officinalis	Shoot	not available	not available	not available	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Mentha spicata	Leaf	not available	not available	not available	Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
Mentha spicata	Shoot	not available	not available	not available	Duke, 1992 *
Mentha x rotundifolia	Tissue Culture	not available	not available	not available	Jim Duke's personal files.
Myristica fragrans	Seed	not available	not available	not available	Chemical Constituents of Oriental Herbs (3 diff. books)
Myroxylon balsamum	Plant	not available	not available	not available	Duke, 1992 *
Nerium oleander	Plant	not available	not available	not available	Duke, 1992 *
Ocimum basilicum	Leaf	not available	1700.0	0.2	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Ocimum basilicum	Flower	not available	1300.0	-0.6	Duke, 1992 *
Ocimum suave	Leaf	not available	not available	not available	J. Nat. Prod. 44: 308.
Ocimum tenuiflorum	Leaf	0.0	2180.0	0.5	Duke, 1992 *
Olea europaea	Hull Husk	not available	not available	not available	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Olea europaea	Petiole	not available	not available	not available	Duke, 1992 *
Origanum majorana	Plant	not available	4700.0	0.2	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Origanum vulgare	Plant	not available	not available	not available	Duke, 1992 *
Panax ginseng	Root	150.0	700.0	0.8	Duke, 1992 *
Panax japonicus	Rhizome	not available	not available	not available	Duke, 1992 *
Panax quinquefolius	Plant	not available	20.0	-1.2	Duke, 1992 *
Panax quinquefolius	Root	600.0	980.0	1.5	Duke, 1992 *
Phoradendron juniperinum	Shoot	not available	3.0	-1.4	Kashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.