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Biological Activity COX-2-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
CIRSIMARITIN IC>50=1,000 uM Duke, 1992 *
CURCUMIN 10-20 uM Duke, 1992 *
CYANIDIN-3-O-GLUCOSIDE IC59=100 ug/ml Duke, 1992 *
EICOSAPENTAENOIC-ACID 1 uM Duke, 1992 *
EMODIN not available Duke, 1992 *
EUGENOL IC50=129 uM Duke, 1992 *
EUGENOL IC>97=1,000 uM Duke, 1992 *
EVODIAMINE 2.5 ug/ml Kang, S. S., Kim, J. S., Son, K. H., Kim, H. P., Chang, H. W. 1999. Cyclooxygenase-2 Inhibitor from Evodia rutaecarpa. Nat. Prod. Sci., 5(2): 65-69.
EVODOL 2.5 ug/ml Kang, S. S., Kim, J. S., Son, K. H., Kim, H. P., Chang, H. W. 1999. Cyclooxygenase-2 Inhibitor from Evodia rutaecarpa. Nat. Prod. Sci., 5(2): 65-69.
FLAVOKAWAIN-B IC16=100 ug/ml Duke, 1992 *
HUMULONE not available Yamamoto, Wang, et al. 2000. Federation of European Biochemical Societies. (per e-mail with Tom Newmark)
ISOTHYMONIN IC>37=1,000 uM Duke, 1992 *
KAEMPFEROL not available Duke, 1992 *
LAURIC-ACID IC20=100 Duke, 1992 *
MELATONIN not available Newmark, T. M. and Schulick, P. 2000. Herbal Cox-2 Inhibition - Nature's Challenge to Arthritis, Cancer & Alzheimer's Disease. Hohm Press, Prescott AZ.
MYRICETIN-3-O-BETA-D-GLUCURONIDE IC50=8 uM/ Hiermann, A., Schramm, H. W., Laufer, S. 1998. Anti-Inflammatory Activity of Myricetin-3--O-beta-d-glucuronide and Related Compounds. Inflamm. Res., 47(11): 421-427.
OLEANOLIC-ACID IC50=295 uM/ Duke, 1992 *
OLEANOLIC-ACID not available Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
PARTHENOLIDE not available Newmark, T. M. and Schulick, P. 2000. Herbal Cox-2 Inhibition - Nature's Challenge to Arthritis, Cancer & Alzheimer's Disease. Hohm Press, Prescott AZ.
PINOSTROBIN IC7=100 ug/ml Duke, 1992 *
List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Aloe vera Bitter Aloes; Aloe 3 20.399999618530273
Aloysia citrodora Lemon Verbena 2 0
Alpinia galanga Greater Galangal; Siamese Ginger; Languas 2 72, 324
Alpinia officinarum Lesser Galangal; Chinese Ginger 3 1, 600
Althaea officinalis Marshmallow; White Mallow 5 0
Amaranthus sp. Pigweed 1 508
Amaranthus spinosus Spiny pigweed 1 408
Ammi majus Bishop's Weed 1 0
Ammi visnaga Visnaga 2 0
Amorphophallus campanulatus Elephant-Foot Yam 1 6.800000190734863
Amorphophallus konjac Devil's Tongue; Konjac; Leopard Palm; Umbrella Arum; Elephant Yam; Snake Palm 1 0
Anacardium occidentale Cashew 3 8, 048.600000023842
Ananas comosus Pineapple 2 3
Anastatica hierochuntica Jericho Rose 1 0
Andira inermis Cabbage Bark 1 0
Anemone pulsatilla Pasque Flower 2 0
Anethum graveolens Dill; Garden Dill 7 5, 712
Angelica archangelica Garden Angelica; Angelica; Wild Parsnip 2 0
Angelica sinensis Dang Gui; Dong Quai; Dang Quai; Dang Qui; Dong Gui; Chinese Angelica 1 7.200000286102295
Anisochilus carnosus Panjiri-ka Pat 1 0