An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Biological Activity COX-2-Inhibitor

Select a Results View:

List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
CIRSIMARITIN IC>50=1,000 uM Duke, 1992 *
CURCUMIN 10-20 uM Duke, 1992 *
CYANIDIN-3-O-GLUCOSIDE IC59=100 ug/ml Duke, 1992 *
EICOSAPENTAENOIC-ACID 1 uM Duke, 1992 *
EMODIN not available Duke, 1992 *
EUGENOL IC>97=1,000 uM Duke, 1992 *
EUGENOL IC50=129 uM Duke, 1992 *
EVODIAMINE 2.5 ug/ml Kang, S. S., Kim, J. S., Son, K. H., Kim, H. P., Chang, H. W. 1999. Cyclooxygenase-2 Inhibitor from Evodia rutaecarpa. Nat. Prod. Sci., 5(2): 65-69.
EVODOL 2.5 ug/ml Kang, S. S., Kim, J. S., Son, K. H., Kim, H. P., Chang, H. W. 1999. Cyclooxygenase-2 Inhibitor from Evodia rutaecarpa. Nat. Prod. Sci., 5(2): 65-69.
FLAVOKAWAIN-B IC16=100 ug/ml Duke, 1992 *
HUMULONE not available Yamamoto, Wang, et al. 2000. Federation of European Biochemical Societies. (per e-mail with Tom Newmark)
ISOTHYMONIN IC>37=1,000 uM Duke, 1992 *
KAEMPFEROL not available Duke, 1992 *
LAURIC-ACID IC20=100 Duke, 1992 *
MELATONIN not available Newmark, T. M. and Schulick, P. 2000. Herbal Cox-2 Inhibition - Nature's Challenge to Arthritis, Cancer & Alzheimer's Disease. Hohm Press, Prescott AZ.
MYRICETIN-3-O-BETA-D-GLUCURONIDE IC50=8 uM/ Hiermann, A., Schramm, H. W., Laufer, S. 1998. Anti-Inflammatory Activity of Myricetin-3--O-beta-d-glucuronide and Related Compounds. Inflamm. Res., 47(11): 421-427.
OLEANOLIC-ACID IC50=295 uM/ Duke, 1992 *
OLEANOLIC-ACID not available Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
PARTHENOLIDE not available Newmark, T. M. and Schulick, P. 2000. Herbal Cox-2 Inhibition - Nature's Challenge to Arthritis, Cancer & Alzheimer's Disease. Hohm Press, Prescott AZ.
PINOSTROBIN IC7=100 ug/ml Duke, 1992 *
List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Annona cherimola Cherimoya 1 0.20000000298023224
Annona diversifolia Llama 1 0.4000000059604645
Annona glabra Pondapple 1 23
Annona muricata Soursop 2 0.6000000238418579
Annona reticulata Custard Apple 1 0.20000000298023224
Annona squamosa Sugar-Apple; Sweetsop 1 0.4000000059604645
Anogeissus latifolia Gum Ghatti 1 0
Apium graveolens Celery 8 7, 659
Apocynum cannabinum Bitterroot; Spreading Dogbane 1 0
Aquilegia vulgaris Columbine 1 0
Arachis hypogaea Groundnut; Peanut 6 778.6800000071526
Araucaria bidwillii Monkey puzzle 2 0
Arbutus unedo Arbutus; Strawberry Tree 1 0
Arctium lappa Gobo; Great Burdock; Burdock 3 7, 635
Arctostaphylos uva-ursi Bearberry; Uva Ursi 7 17, 162
Ardisia japonica Marlberry 1 0
Areca catechu Betel Nut; Pin-Lang 2 180, 000
Argemone mexicana Prickly Poppy 1 410
Armoracia rusticana Horseradish 4 156
Arnica montana Leopard's-Bane; Mountain Tobacco 2 0