An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Biological Activity Antimelanomic

List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
10-HYDROXYCAMPTOTHECIN ED50=0.10 ug/ml J. Ethnopharmacology, 32: 117.
3-(3,3-DIMETHYLALLYL)-5-(3-ACETYL-2,4-DIHYDROXY-5-METHYL-6-METHOXYBENZYL)-PHLORACETOPHENONE IC50=0.7 ug/ml Duke, 1992 *
4-BETA-HYDROXYWITHANOLIDE ED50=0.24 ug/ml J. Ethnopharmacology, 32: 117.
7-HYDROXY-6-HYDROMELODIENOL ED50=1.04-1.10 ug/ml Duke, 1992 *
9-METHOXYCAMPTOTHECIN not available Duke, 1992 *
ACRONYCINE not available Collins, D.J., Culvenor, C.C.J., Lamberton, J.A., Loder, J.W. and Price, J.R., Plants for Medicines, CSIRO, East Melbourne, Australia, 1990, 303 pp.
AKAGERINE 1-10 ug/ml Duke, 1992 *
ALLAMANDIN not available Duke, 1992 *
ALLAMCIN not available Duke, 1992 *
APIGENIN 1-50 uM Duke, 1992 *
AZELAIC-ACID not available Duke, 1992 *
BETA-IONONE IC50=140 uM/l Duke, 1992 *
BETULINIC-ACID not available New York Times, 3/28/95.
BRUCEANTIN ED50=0.001 ug/ml J. Ethnopharmacology, 32: 117.
BRUCEANTINOL not available Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
CAMPTOTHECIN ED50=0.14 ug/ml J. Ethnopharmacology, 32: 117.
CARVACROL IC50=120 uM/l Duke, 1992 *
COLCHICINE ED50=0.18 ug/ml J. Ethnopharmacology, 32: 117.
COUMARIN 50 mg/day Duke, 1992 *
CURCUMIN 200 nM/kg orl mus Duke, 1992 *
List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Hyptis emoryi Desert Lavender 1 0
Hyptis suaveolens Wild Hops 2 8
Hyptis verticillata Barrehorno; John Charles 1 1, 000
Hyssopus officinalis Hyssop 6 60, 432
Ilex paraguariensis Mate; Paraguay Tea; South American Holly 1 0
Illicium verum Star Anise; Chinese Star Anise; Chinesischer Sternanis (Ger.); Sternanis (Ger.); anis de China (Sp.); anis estrellado (Sp.) 3 0
Inga punctata not available 1 0
Inula helenium Elecampane 2 0
Ipomoea aquatica Swamp Cabbage; Water Spinach 1 2, 360
Ipomoea batatas Sweet Potato 2 121
Iris missouriensis not available 1 0
Iris x germanica Orris 1 0
Isatis tinctoria Dyer's Woad 1 0
Jacaranda caucana not available 1 110
Jasminum officinale Jasmine; Poet's Jessamine 2 760
Jasminum sambac not available 1 100
Jateorhiza palmata Calumba Root 1 0
Jatropha gossypifolia Spanish Physic Nut 1 0
Juglans cinerea Butternut 1 0.10000000149011612
Juglans nigra Black Walnut 5 36, 003.01999999955