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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
  1. Home
  2. COLCHICINE

COLCHICINE

Chemical ID
COLCHICINE
Ubiquitous
No
List of known dosages
Dosage Reference
LD50=1.6 (ivn rat)
LD50=4.13 (ivn mus) Merck 11th Edition
LDlo=0.186 (orl hmn) CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses
LDlo=7 mg/man Martindale's 29th
LD50=0.13 (orl cat) Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
LD50=66.6 (orl mus) Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Antiamyloidosic Martindale's 29th
Antiarthritic *
Antibacterial *
AntiBehcet's Martindale's 28th
Anticirrhotic 1-2 mg/man/day Martindale's 28th
Antidermatitic Martindale's 29th
Antierythemic Martindale's 29th
Antiherpetic *
AntiHIV EC50=0.01 uM *
Antiinflammatory *
Antileukemic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antimalarial 500 ug/10x/day/man Martindale's 28th
Antimelanomic ED50=0.18 ug/ml J. Ethnopharmacology, 32: 117.
Antimeningitic 500 ug/2x/man/day Martindale's 28th
Antimitotic 2 mg/kg scu mus Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
AntiPaget's 600 ug/3x/day/man Martindale's 29th
Antipericarditis 500-1,000 ug/man/day *
Antipodagric 3-6mg man/day/ Martindale's 28th
Antipolyserositic 500-600 ug/2-3 x day/man/ Martindale's 28th
Antipsoriac Martindale's 28th
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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name Plant Part Low Parts Per Million High Parts Per Million Standard Deviation Reference
Colchicum autumnale Tuber 800.0 12300.0 *
Gloriosa superba Bulb *