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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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BRUCEANTIN

Chemical ID
BRUCEANTIN
Ubiquitous
No
List of known dosages
Dosage Reference
LD50=1.9-2.6 (ivn mus) Merck 11th Edition
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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Amebicide IC50=0.035 uM *
Antibacterial IC9=12.5 ug/ml *
Antifeedant *
Antigiardial IC50=1.2 uM *
Antileukemic Merck 11th Edition
Antimalarial IC50=0.8 ng/ml *
Antimelanomic ED50=0.001 ug/ml J. Ethnopharmacology, 32: 117.
Antisarcomic ED50=0.0014 ug/ml J. Ethnopharmacology, 32: 117.
Antiseptic IC9=12.5 ug/ml *
Antitubercular IC9=12.5 ug/ml *
Antitumor (Breast) ED50=0.003 ug/ml Cordell, G.A., Beecher, C.W.W., and Pezzuto, J.M. Can ethnopharmacology contribute to the development of new anticancer drugs? Journal of Ethnopharmacology, 32: 117-133, 1991.
Antitumor (Colon) ED50=0.0074 ug/ml Cordell, G.A., Beecher, C.W.W., and Pezzuto, J.M. Can ethnopharmacology contribute to the development of new anticancer drugs? Journal of Ethnopharmacology, 32: 117-133, 1991.
Cytotoxic 1 ppb *
Cytotoxic (KB) IC50=0.015 uM *
Mycobactericide IC9=12.5 ug/ml *
Pesticide *
Plasmodicide IC50=0.0015 uM *
Pyrogenic 5.5 mg/sq m body, ivn hmn Garnick, M. B., Blum, R. H., Canellos, G. P., Mayer, R. J., Parker, L., Skarin, A. T., Li, F. P., Henderson, I. C., Frei III, E. 1979. Phase I Trial of Bruceantin. Cancer Treat Rep, 63: 1929-1932.
Trypanocide IC50=0.0015 uM *