Biological Activity Antimalarial

List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)

Chemical Name Sort descending	Dosage	Reference
ARTEMISININ	ED95=1,000 mg/man/day	Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
ARTEMISININ	IC50=1.4 nM or 0.0014 uM (ED95=1,000 mg/man/day)	Duke, 1992 *
ARTEMISININ	ED50=90 mg/kg orl mus	Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
ARTESUNATE	not available	Duke, 1992 *
ASCARIDOLE	0.05-0.1 uM	Duke, 1992 *
ASIMICIN	IC50=4 ppm	Rupprect, J. K., Hui, Y. H., and McLaughlin, J. L., Annonaceous acetogenins: a review, J. Nat. Prod, 53(2), 1990, 237-238.
ATALAPHILLININE	50 mg/kg/day ipr mus	Duke, 1992 *
ATAPHILLININE	50 mg/kg (ipr mus)	Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
AUGUSTINE	IC50=0.14-0.18 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
AZADIRADIONE	IC50=3 ug/ml	Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982.
AZADIRONE	IC50=12 ug/ml	Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982.
BEBEERINE	not available	Merck 11th Edition
BENZOISOQUINOLONE-5-10-DIONE	IC50=0.84 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BERBERASTINE	50 uM	Duke, 1992 *
BERBERASTINE	0.14-0.36 ug/ml	Duke, 1992 *
BERBERINE	0.14-0.36 ug/ml	Duke, 1992 *
BERBERINE	50 uM	Duke, 1992 *
BETA-DICHROINE	not available	Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
BETA-SELINENE	IC50=>50 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BETA-SELININE-HYDROPEROXIDE	5.6 ug/ml	Duke, 1992 *