Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture

Biological Activity Antimalarial

Select a Results View:

Download these results as:
CSV
XLSX
List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
ARTEMISININ IC50=1.4 nM or 0.0014 uM (ED95=1,000 mg/man/day) *
ARTEMISININ ED50=90 mg/kg orl mus Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
ARTEMISININ ED95=1,000 mg/man/day Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
ARTESUNATE *
ASCARIDOLE 0.05-0.1 uM *
ASIMICIN IC50=4 ppm Rupprect, J. K., Hui, Y. H., and McLaughlin, J. L., Annonaceous acetogenins: a review, J. Nat. Prod, 53(2), 1990, 237-238.
ATALAPHILLININE 50 mg/kg/day ipr mus *
ATAPHILLININE 50 mg/kg (ipr mus) Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
AUGUSTINE IC50=0.14-0.18 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
AZADIRADIONE IC50=3 ug/ml Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982.
AZADIRONE IC50=12 ug/ml Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982.
BEBEERINE Merck 11th Edition
BENZOISOQUINOLONE-5-10-DIONE IC50=0.84 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BERBERASTINE 50 uM *
BERBERASTINE 0.14-0.36 ug/ml *
BERBERINE 0.14-0.36 ug/ml *
BERBERINE 50 uM *
BETA-DICHROINE Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
BETA-SELINENE IC50=>50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BETA-SELININE-HYDROPEROXIDE 5.6 ug/ml *
Download these results as:
CSV
XLSX
List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Terminalia bellirica Beleric Myrobalan; Bahera; Myrobalan Belleric; Myrobalan; Belleric 2 0
Terminalia catappa Indian Almond; Tropical Almond; Malabar Almond 5 14, 437.5
Terminalia chebula Ink Nut; Myrobalan; Black Myrobalan; Chebulic Myrobalan 4 210, 516
Terminalia ivorensis Idigbo; Emire; Blackbark; Black Afara; Brimstonewood; Satinwood; Shinglewood 2 0
Terminalia pallida 2 0
Ternstroemia gymnanthera 2 0
Ternstromia merriliana 1 20, 000
Tetracera akara 1 10, 500
Tetracera indica 1 6, 000
Tetracera sarmentosa 1 12, 300
Tetracera scandens 1 13, 500
Teucrium arduini 'Croatian Alpine' Germander 1 116
Teucrium botrys Field Germander 1 0
Teucrium chamaedrys Wall Germander 1 0
Teucrium cyprium 'Cyprus' Germander 3 465
Teucrium divaricatum Hoary Divaricate Germander 3 42
Teucrium gnaphalodes Iberian Germander 2 67
Teucrium kotschyanum Stavros Kotschy's Germander 3 300
Teucrium micropodioides Small 'Cyprus' Germander 3 188
Teucrium montanum Mountain Germander 1 0