Chemical BERBERINE | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

BERBERINE

Ubiquitous

List of known dosages
Dosage	Reference
LD50=100 mg/kg
LD50=24 mg/kg (ipr mus)
LD50=329 (orl mus)
LD50=10-20 (ivn dog)
LD50=27.5 mg/kg man
LD50=>1,000 mg/kg (orl rat)
LD50=8.2 mg/kg (ivn mus)	Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD50=26.4 mg/kg (ipr mus)	Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD50=13.2 mg/kg (scu mus)	Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.

Download these results as:

CSV

EXCEL

PDF

List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
(+)-Inotropic	not available	Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Abortifacient	not available	Duke, 1992 *
Adrenolytic	not available	Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Amebicide	200 ug/ml	Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Amebicide	EC83=100 ug/ml orl rat	Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Analgesic	not available	Duke, 1992 *
Anesthetic	not available	Duke, 1992 *
Antiacetylcholinesterase	not available	Duke, 1992 *
Antiacne	not available	Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Antiadrenergic	not available	Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antiaggregant	not available	Duke, 1992 *
Antialzheimeran	not available	Duke, 1992 *
Antiamnesic	not available	Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Antiangiogenic	not available	Duke, 1992 *
Antiarrhythmic	not available	Duke, 1992 *
Antiarthritic	not available	Duke, 1992 *
Antibacillus	MIC=200 ug/ml	Duke, 1992 *
Antibacterial	12.5-2,500 ug/ml	Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antibacterial	100 mg/4x/day	Duke, 1992 *
Antibacterial	MIC=6-630 ug/ml	Duke, 1992 *

Download these results as:

CSV

EXCEL

PDF

List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Adonis vernalis	Plant	not available	not available	not available	Duke, 1992 *
Andira inermis	Bark	not available	not available	not available	Duke, 1992 *
Argemone mexicana	Plant	not available	410.0	not available	Duke, 1992 *
Berberis vulgaris	Root Bark	25000.0	80000.0	not available	Duke, 1992 *
Berberis vulgaris	Stem Bark	20000.0	25000.0	1.0	Jim Duke's personal files.
Berberis vulgaris	Flower	not available	6600.0	not available	Jim Duke's personal files.
Berberis vulgaris	Stem	1600.0	28900.0	not available	Jim Duke's personal files.
Berberis vulgaris	Leaf	not available	3000.0	1.0	Jim Duke's personal files.
Berberis vulgaris	Plant	not available	not available	not available	Jim Duke's personal files.
Berberis vulgaris	Root	4000.0	64800.0	1.1	Duke, 1992 *
Berberis vulgaris	Bark	not available	45000.0	1.0	Jim Duke's personal files.
Caulophyllum thalictroides	Plant	not available	not available	not available	Jim Duke's personal files.
Chelidonium majus	Plant	not available	not available	not available	Duke, 1992 *
Coptis chinensis	Rhizome	40000.0	90000.0	0.9	Duke, 1992 *
Coptis japonica	Rhizome	40000.0	70000.0	-0.3	Duke, 1992 *
Coptis spp	Rhizome	40000.0	90000.0	0.9	Duke, 1992 *
Corydalis spp	Plant	not available	not available	not available	Duke, 1992 *
Eschscholzia californica	Shoot	not available	not available	not available	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Hydrastis canadensis	Root	1385.0	60000.0	0.9	Duke, 1992 *
Hydrastis canadensis	Plant	not available	not available	not available	Duke, 1992 *