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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
ANCISTROBERTSONINE-D IC50=4.8 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANCISTROBREVINE IC50=5-25 ug/ml *
ANCISTROBREVINE-B IC50=2-4.7 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANCISTROCLADINE IC50=5-25 ug/ml *
ANCISTROHEYNINE-A IC50=2.1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANCISTROLIKOKINE-A IC50=0.14-0.19 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANCISTROLIKOKINE-B IC50=0.21-0.54 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANCISTROLIKOKINE-C IC50=0.62-0.92 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANHYDROLYCORINE IC50=6.1-6.4 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANNONACIN IC50=1.3-1.5 ppm Rupprect, J. K., Hui, Y. H., and McLaughlin, J. L., Annonaceous acetogenins: a review, J. Nat. Prod, 53(2), 1990, 237-238.
ANOLIGNAN IC50=20 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
APIOLE *
ARBORININE IC50=8.5 ug/ml Khalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986.
AROMOLINE IC50=0.67 ug/ml (ca 1/5 chloroquine) *
ARTARINE *
ARTEANNUIN *
ARTEINCULTON IC50=7.5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ARTEMETHER Merck 11th Edition
ARTEMETIN (Synergic w artemisinin) IC50=26 uM *
ARTEMISINE *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Shorea trapezifolia 1 0
Shorea zeylanica 1 0
Sideritis scardica Balkan Sideritis 2 38
Sideritis sp 1 0
Silybum marianum Milk Thistle; Lady's Thistle 1 0
Simaba multiflora Cajurana 1 0
Simarouba glauca Simaruba Bark 2 0
Skimmia arborescens Skimmia 2 500
Skimmia japonica Japanese Skimmia 1 0
Smilax china China Root 1 0
Solanum aviculare 1 30, 000
Solanum laciniatum 1 0
Solanum tuberosum Potato 2 0
Solidago gigantea Early Goldenrod 2 0
Solidago virgaurea European Goldenrod; Woundwort 2 0
Sophora japonica Japanese Pagoda Tree 3 434, 000
Sophora subprostrata Shan Dou Gen 1 0
Sorbus aucubaria Rowan Berry 3 0
Sorocea bonplandii 1 13.100000381469727
Spartium junceum Genet; Spanish Broom; Weaver's Broom 2 0