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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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ARTEMISININ

Chemical ID
ARTEMISININ
Ubiquitous
No
List of known dosages
Dosage Reference
LD50=2,571 (ims rat) Merck 11th Edition
LD50=2,800-3,840 (ims mus)
LD50=4,228-5,105 (orl mus)
LD50=5,576 (orl rat)
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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Antimalarial ED50=90 mg/kg orl mus Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antimalarial ED95=1,000 mg/man/day Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antimalarial IC50=1.4 nM or 0.0014 uM (ED95=1,000 mg/man/day) *
Antitumor *
Antiviral Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991.
Calcium-Antagonist IC50=190 uM gpg *
Cytotoxic IC50=30 uM *
Herbicide IC50=33 uM Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Immunomodulator *
MDR-Inhibitor IC50=2 uM *
Neurotoxic *
Pesticide *
Plasmodicide IC50=1.4 nM *
Schizonticide MIC=0.1 uM *
Teratogenic Martindale's 29th
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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name Plant Part Low Parts Per Million High Parts Per Million Standard Deviation Reference
Artemisia annua Flower 100.0 5000.0 Father Nature's Farmacy: The aggregate of all these three-letter citations.
Artemisia annua Leaf 10.0 13800.0 *