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Chemical ARTEMISININ

Chemical ID
ARTEMISININ
Ubiquitous
No
List of known dosages
Dosage Reference
LD50=2,571 (ims rat) Merck 11th Edition
LD50=2,800-3,840 (ims mus)
LD50=4,228-5,105 (orl mus)
LD50=5,576 (orl rat)

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Sort descending Dosage Reference
Antimalarial ED50=90 mg/kg orl mus Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antimalarial ED95=1,000 mg/man/day Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antimalarial IC50=1.4 nM or 0.0014 uM (ED95=1,000 mg/man/day) Duke, 1992 *
Antitumor not available Duke, 1992 *
Antiviral not available Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991.
Calcium-Antagonist IC50=190 uM gpg Duke, 1992 *
Cytotoxic IC50=30 uM Duke, 1992 *
Herbicide IC50=33 uM Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Immunomodulator not available Duke, 1992 *
MDR-Inhibitor IC50=2 uM Duke, 1992 *
Neurotoxic not available Duke, 1992 *
Pesticide not available Duke, 1992 *
Plasmodicide IC50=1.4 nM Duke, 1992 *
Schizonticide MIC=0.1 uM Duke, 1992 *
Teratogenic not available Martindale's 29th
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