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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
3-METHYLNAPHTHARAZIN IC50=5.8 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
3-O-BENZOYLHOSLOPPONE IC50=0.4 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
4,7-DIMETHYL-1-TETRALONE EC50=>3-100 uM *
5,6,7-TRIMETHOXYCOUMARIN IC50=1ug/ml *
5,7-DIMETHOXY-8-(3'-HYDROXY-3'-METHYL-1'-BUTENE) IC50=8.8-16.25 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
6'-DESMETHYL-THALIFABORAMINE IC50=0.01-0.15 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
6-ACETYLSWIETENOLIDE IC50=7.5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
6-ALPHA-TIGLOYLOXYGLAUCARUBOL IC50=0.257 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
7-DEACETYLGEDUNIN IC50=3.6 ug/ml Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982.
7-DEACETYLKHIVORIN IC50=5 ug/ml *
7-EPIDIONCHOPHYLLINE-A IC50=0.2 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
7-METHOXY-BETA-CARBOLINE-1-PROPIONIC-ACID IC50=0.3-2.9 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
7-O-DEMETHYLTETRANDRINE IC50=0.74 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
8-EPIXANTHIN IC50=125 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
8-EPIXANTHIN-1,5-EPOXIDE IC50=7.8 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ACACETIN IC50=4.2-12.6 ug/ml *
AFFINISINE IC50=5->5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
AILANTHINONE IC50=0.025 uM *
AILANTHONE Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
AJOENE 50 mg/kg *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Tovomita pyrifolia 1 0
Triadenum japonicum 1 0
Tribulus terrestris Puncture-vine 3 0
Tridax procumbens Coatbuttons; Mexican daisy 1 0
Trifolium pratense Red Clover; Purple Clover; Peavine Clover; Cowgrass 2 168
Trigonella foenum-graecum Fenugreek; Greek Clover; Greek Hay; Bockshornklee (Ger.); Alholva (Sp.) 2 0
Trilisa odoratissima Carolina Vanilla; Deer's Tongue; Hound's Tongue; Vanilla Plant 1 0
Tripterygium wilfordiim Yellow Vine 1 0
Triticum aestivum Wheat 1 0
Tussilago farfara Coltsfoot 2 3, 600
Ulex europaeus Gorse 1 0
Umbellularia californica California Bay 1 40
Uncaria catechu Gambir; Pale Catechu 2 0
Uncaria guianensis Cat's Claw; Una de Gato; Garabato Colorado; Tambor Huasca; Ungunagi 2 0
Uncaria tomentosa Cat's Claw; Garabato Amarillo; Una de Gato 5 33, 480
Urginea maritima European Squill 1 0
Urtica dioica European Nettle; Stinging Nettle 4 26, 070
Uvaria sp. 2 0
Vaccinium corymbosum Blueberry 5 0
Vaccinium macrocarpon Cranberry; Large Cranberry; American Cranberry 3 750