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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
3-METHYLNAPHTHARAZIN IC50=5.8 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
3-O-BENZOYLHOSLOPPONE IC50=0.4 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
4,7-DIMETHYL-1-TETRALONE EC50=>3-100 uM *
5,6,7-TRIMETHOXYCOUMARIN IC50=1ug/ml *
5,7-DIMETHOXY-8-(3'-HYDROXY-3'-METHYL-1'-BUTENE) IC50=8.8-16.25 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
6'-DESMETHYL-THALIFABORAMINE IC50=0.01-0.15 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
6-ACETYLSWIETENOLIDE IC50=7.5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
6-ALPHA-TIGLOYLOXYGLAUCARUBOL IC50=0.257 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
7-DEACETYLGEDUNIN IC50=3.6 ug/ml Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982.
7-DEACETYLKHIVORIN IC50=5 ug/ml *
7-EPIDIONCHOPHYLLINE-A IC50=0.2 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
7-METHOXY-BETA-CARBOLINE-1-PROPIONIC-ACID IC50=0.3-2.9 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
7-O-DEMETHYLTETRANDRINE IC50=0.74 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
8-EPIXANTHIN IC50=125 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
8-EPIXANTHIN-1,5-EPOXIDE IC50=7.8 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ACACETIN IC50=4.2-12.6 ug/ml *
AFFINISINE IC50=5->5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
AILANTHINONE IC50=0.025 uM *
AILANTHONE Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
AJOENE 50 mg/kg *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Teucrium polium Iberian Golden Germander; Golden Germander 4 68
Teucrium scordium Water Germander 3 0
Teucrium scorodonia Germander; Wood Germander 2 6, 000
Theobroma cacao Cacao 2 0
Thespesia populnea Indian tulip tree 2 78, 800
Thevetia peruviana Peruvian Yellow Oleander; Luckynut; Yellow Oleander; Oleandre Jaune (Fr.); Thevetie (Ger.); Loandro-Amarelo (Port.); Adelfa Amarilla (Sp.); Cabalonga (Sp.); Chirca (Sp.) 3 13, 500
Thymus broussonettii Moroccan Thyme 1 0
Thymus capitatus 'Sicilian' Thyme; Spanish Origanum; Spanish Thyme 1 0
Thymus cilicicus 'Anatolian' Thyme 3 141
Thymus funkii Funk's Thyme 3 53
Thymus longicaulis Kekik; Tas Kekik 1 0
Thymus mastichina Spanish Marjoram 1 75
Thymus saturejoides Moroccan Savory Thyme 1 10
Thymus serpyllum Creeping Thyme 2 13, 900
Thymus vulgaris Common Thyme; Garden Thyme; Thyme 3 75, 300
Thymus zygis Spanish Thyme 1 0
Tilia sp. Basswood; Lime; Linden 1 0
Tovomita brasiliensis 1 0
Tovomita excelsa 1 83.9000015258789
Tovomita mangle 1 0