Biological Activity Antimalarial | Dr. Duke's Phytochemical and Ethnobotanical Databases

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name	Dosage	Reference
OPHIOBOLIN-A	IC50=0.5-0.6 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
OSTHOL	IC50=25.1 ug/ml	Khalid, S.A., Farouk, A., Geary*, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum. Journal of Ethnopharmacology, 15: 201-209, 1986.
OSTHOLE	not available	Duke, 1992 *
OSTRUTHIN	not available	Duke, 1992 *
OXYACANTHINE	IC50=0.3 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PALMATINE	not available	Duke, 1992 *
PATCHOULENE	IC50=108 uM	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PHAEANTHINE	IC50=1.43 ug/ml (1/10 x chloroquine)	Duke, 1992 *
PHEANTHINE	IC50=1,400 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PHLORIDZIN	not available	Duke, 1992 *
PHLORIZIN	not available	Duke, 1992 *
PIQUEROL-A	IC50=100 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PLEIOCARPAMINE	IC50=6-20 uM	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PLUMBAGIN	IC50=0.178-0.189 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PLUMBAGIN	IC50=0.3 uM	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PRIEURIANIN	IC50=14.08 ug/mL)	Duke, 1992 *
PRISTIMERIN	IC50=0.19-28 ug/ml	Duke, 1992 *
PSYCHOTRINE	IC50=0.1-0.4 uM	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PUNICALAGIN	2-8 ug/ml	Duke, 1992 *
PYCNAMINE	IC50=0.15 ug/mL (ca 1 x chloroquine)	Duke, 1992 *

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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name	Common Name	Chemical Count	Total Parts Per Million
Panax ginseng	Chinese Ginseng; Oriental Ginseng; Ginseng; Korean Ginseng	6	498, 800
Panax japonicus	Japanese Ginseng	1	0
Panax notoginseng	Sanchi Ginseng	1	0
Panax quinquefolius	American Ginseng; Ginseng	4	2, 000
Pancratium maritimum	Sea Daffodil	1	0
Papaver somniferum	Opium Poppy; Poppyseed Poppy	1	0
Passiflora incarnata	Manzana de Mayo; Mayapple; Passionflower	4	210
Pastinaca sativa	Parsnip	2	0
Pausinystalia johimbe	Yohimbe	4	0
Pedicularis longiflora	not available	1	0
Peganum harmala	Harmel; Syrian Rue	2	0
Pelargonium citrosum	Citrosa	1	2
Pelargonium graveolens	Rose Geranium; Scented Geranium	1	0
Peperomia pelucida	Pepper elder; Yerba de la plata	1	0
Perilla frutescens	Perilla	1	0
Persea americana	Avocado	1	0
Petasites hybridus	European Butterbur	1	0
Petroselinum crispum	Parsley	6	171, 386.67999994755
Peucedanum ostruthium	Masterwort	2	15, 000
Peumus boldus	Boldo	4	12, 470