Biological Activity Antimalarial | Dr. Duke's Phytochemical and Ethnobotanical Databases

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name	Dosage	Reference
OPHIOBOLIN-A	IC50=0.5-0.6 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
OSTHOL	IC50=25.1 ug/ml	Khalid, S.A., Farouk, A., Geary*, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum. Journal of Ethnopharmacology, 15: 201-209, 1986.
OSTHOLE	not available	Duke, 1992 *
OSTRUTHIN	not available	Duke, 1992 *
OXYACANTHINE	IC50=0.3 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PALMATINE	not available	Duke, 1992 *
PATCHOULENE	IC50=108 uM	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PHAEANTHINE	IC50=1.43 ug/ml (1/10 x chloroquine)	Duke, 1992 *
PHEANTHINE	IC50=1,400 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PHLORIDZIN	not available	Duke, 1992 *
PHLORIZIN	not available	Duke, 1992 *
PIQUEROL-A	IC50=100 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PLEIOCARPAMINE	IC50=6-20 uM	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PLUMBAGIN	IC50=0.178-0.189 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PLUMBAGIN	IC50=0.3 uM	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PRIEURIANIN	IC50=14.08 ug/mL)	Duke, 1992 *
PRISTIMERIN	IC50=0.19-28 ug/ml	Duke, 1992 *
PSYCHOTRINE	IC50=0.1-0.4 uM	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PUNICALAGIN	2-8 ug/ml	Duke, 1992 *
PYCNAMINE	IC50=0.15 ug/mL (ca 1 x chloroquine)	Duke, 1992 *

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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name	Common Name	Chemical Count	Total Parts Per Million
Ocimum canum	Hoary Basil	3	0
Ocimum gratissimum	Agbo; Shrubby Basil	2	1, 140
Ocimum suave	Kenyan Tree Basil	1	0
Ocimum tenuiflorum	Anise-Scented Basil	3	7, 090
Oenanthe aquatica	Water Fennel; Water Hemlock	1	0
Oenanthe crocata	Water Dropwort	1	0
Oenothera biennis	Evening-Primrose	3	207, 000
Olea europaea	Olive	5	0
Ononis spinosa	Spiny Restharrow; Restharrow; Hauhechel (Ger.)	1	0
Opopanax chironium	Hercules All Heal; Opopanax	1	0
Opuntia ficus-indica	Indian Fig; Prickly Pear; Nopal; Nopalito	1	0
Origanum compactum	not available	1	70
Origanum majorana	Marjoram; Sweet Marjoram	4	13, 600
Origanum onites	Oregano; Pot Marjoram	1	40
Origanum vulgare	Common Turkish Oregano; Wild Oregano; Oregano; Pot Marjoram; Wild Marjoram; European Oregano	4	18, 600
Paeonia japonica	not available	1	5, 000
Paeonia lactiflora	Chih-Shao; Peony; Common Garden Peony; White Peony; Bai Shao (Chinese)	1	0
Paeonia moutan	Moutan; Tree Peony	1	0
Paeonia suffruticosa	Moutan; Tree Peony; Moutan Peony	1	0
Palaquium grande	not available	1	7