Biological Activity Antimalarial | Dr. Duke's Phytochemical and Ethnobotanical Databases

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name	Dosage	Reference
OPHIOBOLIN-A	IC50=0.5-0.6 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
OSTHOL	IC50=25.1 ug/ml	Khalid, S.A., Farouk, A., Geary*, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum. Journal of Ethnopharmacology, 15: 201-209, 1986.
OSTHOLE	not available	Duke, 1992 *
OSTRUTHIN	not available	Duke, 1992 *
OXYACANTHINE	IC50=0.3 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PALMATINE	not available	Duke, 1992 *
PATCHOULENE	IC50=108 uM	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PHAEANTHINE	IC50=1.43 ug/ml (1/10 x chloroquine)	Duke, 1992 *
PHEANTHINE	IC50=1,400 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PHLORIDZIN	not available	Duke, 1992 *
PHLORIZIN	not available	Duke, 1992 *
PIQUEROL-A	IC50=100 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PLEIOCARPAMINE	IC50=6-20 uM	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PLUMBAGIN	IC50=0.3 uM	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PLUMBAGIN	IC50=0.178-0.189 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PRIEURIANIN	IC50=14.08 ug/mL)	Duke, 1992 *
PRISTIMERIN	IC50=0.19-28 ug/ml	Duke, 1992 *
PSYCHOTRINE	IC50=0.1-0.4 uM	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PUNICALAGIN	2-8 ug/ml	Duke, 1992 *
PYCNAMINE	IC50=0.15 ug/mL (ca 1 x chloroquine)	Duke, 1992 *

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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name	Common Name	Chemical Count	Total Parts Per Million
Abelmoschus esculentus	Okra	2	70
Abelmoschus moschatus	Ambrette; Musk Okra; Tropical Jewel Hibiscus; Muskmallow	1	0
Abutilon theophrasti	Velvet Leaf; Butterprint; Indian-Mallow; Abutilon-Hemp	1	0
Acacia catechu	Black Cutch; Catechu	2	0
Acacia decurrens	Green Wattle	1	0
Acacia farnesiana	Cassie; Huisache; Sweet Acacia; Opopanax; Popinac	2	0
Acacia nilotica	Babul	3	0
Acacia senegal	Gum Arabic; Gum Arabic Tree; Kher; Senegal Gum; Sudan Gum Arabic	1	0
Achillea millefolium	Yarrow; Milfoil	7	13, 244
Achyranthes aspera	Chaff Flower	1	0
Achyranthes bidentata	Chaff Flower	1	0
Acinos suaveolens	not available	1	430
Acrotrema arnottianum	not available	1	5, 300
Acrotrema uniflorum	not available	1	2, 400
Actinidia chinensis	Kiwi	1	0
Adansonia digitata	not available	1	0
Adiantum capillus-veneris	Maidenhair Fern	1	0
Adonis vernalis	Spring Adonis	1	0
Aegle marmelos	Bael de India; Bael fruit	1	0
Aesculus hippocastanum	Horse Chestnut	2	0