Biological Activity Antimalarial | Dr. Duke's Phytochemical and Ethnobotanical Databases

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name	Dosage	Reference
OPHIOBOLIN-A	IC50=0.5-0.6 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
OSTHOL	IC50=25.1 ug/ml	Khalid, S.A., Farouk, A., Geary*, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum. Journal of Ethnopharmacology, 15: 201-209, 1986.
OSTHOLE	not available	Duke, 1992 *
OSTRUTHIN	not available	Duke, 1992 *
OXYACANTHINE	IC50=0.3 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PALMATINE	not available	Duke, 1992 *
PATCHOULENE	IC50=108 uM	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PHAEANTHINE	IC50=1.43 ug/ml (1/10 x chloroquine)	Duke, 1992 *
PHEANTHINE	IC50=1,400 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PHLORIDZIN	not available	Duke, 1992 *
PHLORIZIN	not available	Duke, 1992 *
PIQUEROL-A	IC50=100 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PLEIOCARPAMINE	IC50=6-20 uM	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PLUMBAGIN	IC50=0.3 uM	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PLUMBAGIN	IC50=0.178-0.189 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PRIEURIANIN	IC50=14.08 ug/mL)	Duke, 1992 *
PRISTIMERIN	IC50=0.19-28 ug/ml	Duke, 1992 *
PSYCHOTRINE	IC50=0.1-0.4 uM	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PUNICALAGIN	2-8 ug/ml	Duke, 1992 *
PYCNAMINE	IC50=0.15 ug/mL (ca 1 x chloroquine)	Duke, 1992 *

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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name	Common Name	Chemical Count	Total Parts Per Million
Lycoris squamigera	Magic Lily; Resurrection Lily	1	0
Lythrum salicaria	Purple Loosestrife	1	0
Machaerocereus gummosus	not available	1	4, 000
Macleaya cordata	Plume Poppy	1	0
Maclura pomifera	Osage-Orange; Hedge Apple	4	7, 928
Madhuca microphylla	not available	1	930
Madhuca nerifolia	not available	1	560
Magnolia denudata	Hsin-I; Xin-Yi	3	0
Magnolia kobus	Hsin-I; Xin-Yi	2	1, 000
Magnolia officinalis	Chinese Magnolia; Hou Pu; Magnolia-Bark	1	0
Mahonia aquifolium	Oregon Grape; Blue Barberry; Holly Barberry; Holly Mahonia; Mountain Grape	8	195
Mahonia bealei	not available	1	5, 000
Mahonia fargesii	not available	3	0
Mahonia fortunei	not available	2	0
Mahonia gracilipes	not available	4	0
Mahonia japonica	Japanese Ashberry; Hiiragi-Nanten	4	0
Mahonia nervosa	Oregon Barberry; Oregon Grape-Holly; Oregon Grape; Water Holly	1	0
Mahonia philipinensis	not available	2	0
Mahonia repens	Creeping Barberry; Oregon Barberry; Oregon Grape-Holly; Oregon Grape	6	11, 588
Mahonia siamensis	not available	2	4, 600