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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
HEXAMETHOXYLIGNAN IC50=37-50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
HOMOHARRINGTONINE Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
HUMULENE IC50=86 ug/ml *
HYDRANTHINE-A IC50=0.1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
HYDROQUINIDINE Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
HYDROQUINONE *
HYDROXYCRYPTOLEPINE IC50=77-102 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ICAJINE IC50=>80-95 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOCHONDRODENDRINE IC50=892 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOCRYPTOLEPINE IC50=0.8 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOFEBRIFUGINE IC50=0.002-0.003 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOFRAXIDIN IC50=7.95 ug/ml *
ISOIGUESTEROL IC50=0.023-0.54 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOMELDENIN IC50=50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOSTRYCHNINE IC50=14->20 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOSUNGUCINE IC50=0.3-1.3 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOTETRANDRINE IC50=0.07 ug/ml (2 x chloroquine) *
ISOTETRANDRINE IC50=100 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
JATRORRHIZINE IC50=0.42-1.61 ug/ml *
KHAYANTHONE IC50=50 ug/mL) *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Vaccinium myrtillus Bilberry; Whortleberry; Dwarf Bilberry 5 7, 500
Vaccinium vitis-idaea Cowberry; Lingen; Lingonberry 3 22, 500
Valeriana officinalis Valerian; Common Valerian; Garden-Heliotrope 2 255
Vatica affinis 1 740
Vauquelinia corymbosa 1 41
Vellozia declinans 1 0
Verbascum thapsus Mullein; Velvetplant; Flannelleaf; Flannelplant; Great Mullein 2 0
Verbena officinalis Vervain 2 0
Vernonia cinerea Purple fleabane 1 0
Viburnum opulus Crampbark; European Cranberry Bush; Guelder Rose; Snowballbush 2 0
Viburnum prunifolium Black Haw 2 0
Vigna radiata Green Gram; Mungbean 2 0
Vinca minor Periwinkle; Running-Myrtle 2 100, 800
Viola odorata Common Violet; Sweet Violet 2 40, 000
Viola tricolor Pansy; Wild Violet 2 460, 000
Viscum album European Mistletoe 3 5.400000095367432
Viscum articulatum 1 0
Vismia cayennensis 1 0
Vismia micrantha 1 280
Vitellaria paradoxa Butterseed; Shea Nut; Shea-Butter-Tree; Sheatree; Shea 1 0