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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
(+)-1,2-DEHYDROTELOBINE IC50=0.26-0.31 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-2-N-METHYLTELOBINE IC50=0.09-0.26 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-2-NOR-CEPHARANTHINE IC50=0.05-0.13 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-2-NOR-ISOTETRANDRINE IC50=0.05-0.07 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-2-NOR-OBABERINE IC50=0.05-0.09 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-2-NOR-THALRUGOSINE IC50=0.07-0.13 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-AROMOLINE IC50=0.67 ug/ml (ca 1/5 chloroquine) *
(+)-CEPHARANTHINE IC50=0.14-0.30 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-CRINAMINE IC50=2.8-3.4 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-DEPHNANDRINE IC50=0.06-0.22 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-HOMOAROMOLINE IC50=0.02-0.29 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-ISOTETRANDRINE IC50=0.05-0.17 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-OBABERINE IC50=0.22-0.23 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-STEPHIBABERINE IC50=0.13-0.31 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-TETRANDRINE IC50=0.16-0.18 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(+)-THALRUGOSINE IC50=0.06-0.23 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-ANONAINE IC50=1290-1900 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-ASIMILOBINE IC50=470-950 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-CAPAURINE IC50=1910-4340 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-CASSYTHICINE IC50=2260-2290 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Vaccinium myrtillus Bilberry; Whortleberry; Dwarf Bilberry 5 7, 500
Vaccinium vitis-idaea Cowberry; Lingen; Lingonberry 3 22, 500
Valeriana officinalis Valerian; Common Valerian; Garden-Heliotrope 2 255
Vatica affinis 1 740
Vauquelinia corymbosa 1 41
Vellozia declinans 1 0
Verbascum thapsus Mullein; Velvetplant; Flannelleaf; Flannelplant; Great Mullein 2 0
Verbena officinalis Vervain 2 0
Vernonia cinerea Purple fleabane 1 0
Viburnum opulus Crampbark; European Cranberry Bush; Guelder Rose; Snowballbush 2 0
Viburnum prunifolium Black Haw 2 0
Vigna radiata Green Gram; Mungbean 2 0
Vinca minor Periwinkle; Running-Myrtle 2 100, 800
Viola odorata Common Violet; Sweet Violet 2 40, 000
Viola tricolor Pansy; Wild Violet 2 460, 000
Viscum album European Mistletoe 3 5.400000095367432
Viscum articulatum 1 0
Vismia cayennensis 1 0
Vismia micrantha 1 280
Vitellaria paradoxa Butterseed; Shea Nut; Shea-Butter-Tree; Sheatree; Shea 1 0