Chemical HOMOHARRINGTONINE | Dr. Duke's Phytochemical and Ethnobotanical Databases

Dr. Duke's Phytochemical and Ethnobotanical Databases

U.S. Department of Agriculture

Chemical ID

HOMOHARRINGTONINE

Ubiquitous

No

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
Anticarcinomic	0.25-1 ppm	Duke, 1992 *
Antileukemic	1 ppm	Duke, 1992 *
Antimalarial	not available	Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Antimelanomic	ED50=0.045 ug/ml	J. Ethnopharmacology, 32: 117.
Antisarcomic	ED50=2.15 ug/ml	J. Ethnopharmacology, 32: 117.
Antitumor	not available	Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Antitumor (Breast)	ED50=0.012 ug/ml	J. Ethnopharmacology, 32: 117.
Antitumor (Colon)	ED50=0.0076 ug/ml	J. Ethnopharmacology, 32: 117.
Antitumor (Lung)	ED50=0.019 ug/ml	J. Ethnopharmacology, 32: 117.
Hypotensive	not available	Martindale's 29th
MDR-Inhibitor	not available	Qian, Q. J., Han, J. L., Yan, W. W., Yang, C. Z., Han, D. S., Shi, H., Hao, Y. 1996. A Comparative Study on the Mechanism of Homoharringtonine (HHI) and Melphalan (MEL) Resistance in K562/H20 and K562/MEL Cell Lines. Zhonghua Xueyexue Zazhi,17(7):354-356.
Tachycardic	not available	Martindale's 29th

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Cephalotaxus drupacea	Stem	not available	not available	not available	Duke, 1992 *
Cephalotaxus fortunei	Stem	not available	not available	not available	Duke, 1992 *
Cephalotaxus harringtonii	Tissue Culture	0.0	1.2	not available	Duke, 1992 *
Cephalotaxus spp	Plant	not available	not available	not available	Duke, 1992 *