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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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5-Lipoxygenase-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
ESCULETIN IC50=0.1-5 uM *
FISETIN IC50 (uM)=11 *
GAMMA-BOSWELLIC-ACID *
KAEMPFEROL IC50 (uM)=20 *
MYRCETIN IC50 (uM)=13 *
N-PROPYLSULPHINOTHIOIC-ACID-S-N-PROPYLESTER *
NDGA IC50 (uM)=0.8 *
NORDIHYDROGUAIARETIC-ACID *
OSTHOL *
PARTHENOLIDE *
PROPYL-GALLATE IC50 (uM)=5 *
QUERCETIN IC50 (uM)=4 *
RESVERATROL IC50=1-9 uM *
RESVERATROL IC50=48 uM *
SANGUINARINE Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill
Livinston, Edinburgh.
SHOGAOL *
TRANS-5-ETHYL-4,6,7-TRITHIA-2-DECENE-4-S-OXIDE *
TRANS-METHYLSULPHINOTHIOIC-ACID-S-1-PROPENYLESTER *
TRANS-N-PROPYLSULPHINOTHIOIC-ACID-S-1-PROPENYLESTER *
TRANS-TRANS-5-ETHYL-4,6,7-TRITHIA-2,8-DECADIENE-4-S-OXIDE *
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List of Activity Plants.
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Plant Name Common Name Chemical Count Total Parts Per Million
Sambucus nigra European Alder; European Elder; European Elderberry; Elder; Black Elder 2 0
Sanguinaria canadensis Bloodroot 2 60, 000
Sanguisorba minor Small Burnet 2 0
Sanguisorba officinalis Greater Burnet 2 0
Schinus molle California Peppertree; Mastic-Tree; Peruvian Peppertree 3 0
Schinus terebinthifolius Brazilian Peppertree 2 0
Scopolia carniolica Scopolia 2 0
Scutellaria baicalensis Chinese Skullcap; Huang Qin; Baikal Skullcap 1 163, 200
Scutellaria galericulata Marsh Skullcap 1 0
Scutellaria sp 1 0
Senna occidentalis Coffee Senna 1 0
Serenoa repens Saw Palmetto; Scrub-Palmetto 1 0
Silybum marianum Milk Thistle; Lady's Thistle 2 0
Solanum tuberosum Potato 2 0
Solidago gigantea Early Goldenrod 2 0
Solidago virgaurea European Goldenrod; Woundwort 1 0
Sophora japonica Japanese Pagoda Tree 2 0
Sorbus aucubaria Rowan Berry 1 0
Spartium junceum Genet; Spanish Broom; Weaver's Broom 1 0
Spinacia oleracea Spinach 2 21