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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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  2. 5-Lipoxygenase-Inhibitor

5-Lipoxygenase-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
ESCULETIN IC50=0.1-5 uM *
FISETIN IC50 (uM)=11 *
GAMMA-BOSWELLIC-ACID *
KAEMPFEROL IC50 (uM)=20 *
MYRCETIN IC50 (uM)=13 *
N-PROPYLSULPHINOTHIOIC-ACID-S-N-PROPYLESTER *
NDGA IC50 (uM)=0.8 *
NORDIHYDROGUAIARETIC-ACID *
OSTHOL *
PARTHENOLIDE *
PROPYL-GALLATE IC50 (uM)=5 *
QUERCETIN IC50 (uM)=4 *
RESVERATROL IC50=1-9 uM *
RESVERATROL IC50=48 uM *
SANGUINARINE Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill
Livinston, Edinburgh.
SHOGAOL *
TRANS-5-ETHYL-4,6,7-TRITHIA-2-DECENE-4-S-OXIDE *
TRANS-METHYLSULPHINOTHIOIC-ACID-S-1-PROPENYLESTER *
TRANS-N-PROPYLSULPHINOTHIOIC-ACID-S-1-PROPENYLESTER *
TRANS-TRANS-5-ETHYL-4,6,7-TRITHIA-2,8-DECADIENE-4-S-OXIDE *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Prunus persica Peach 2 0
Prunus serotina Black Cherry; Wild Cherry 2 0
Prunus spinosa Blackthorn; Sloe 2 0
Psidium cattleianum Strawberry Guava 2 0
Psidium guajava Guava 1 200
Pteridium aquilinum Bracken; Bracken Fern 1 0
Pterocarpus marsupium Indian Kino; Malabar Kino; bijasal 1 0
Pueraria montana Kudzu; Kudsu 2 0
Punica granatum Pomegranate; Grenadier (Fr.); Granatapfelbaum (Ger.); Granatapfelstrauch (Ger.); Zakuro (Jap.); Romanzeiro (Port.); Granado (Sp.); Mangrano (Sp.) 2 0
Pyrus communis Pear 1 28
Quercus alba White Oak 1 0
Quercus infectoria Aleppo Oak; Dyer's Oak; Gall Oak 1 0
Quercus robur English Oak 1 0
Quercus velutina Black Oak 1 0
Rheum officinale Chinese Rhubarb 1 3, 437.5
Rheum rhabarbarum Rhubarb 1 0
Rhododendron dauricum Chinese Alpenrose 2 0
Rhododendron ponticum Pontic Alpenrose 1 0
Rhus coriaria Sicilian Sumac; Sumac; Tanner's Sumac 1 0
Rhus glabra Smooth Sumac 1 0