An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Chemical COUMARIN

Chemical ID
COUMARIN
Ubiquitous
No
List of known dosages
Dosage Reference
LD50=202 (orl gpg) Merck 11th Edition
LD50=293 (orl rat) CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses, Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
LD50=680 (orl rat) Merck 11th Edition
LD50=720 (orl rat)
List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Antipsittacotic not available Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill
Livinston, Edinburgh.
Antipsoriac not available Pandeya, S.N. 1970. Biological Activity of Adamantyl Derivatives. The Indian Journal of Pharmacy, 33: 7.
Antitoxoplasmotic not available Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill
Livinston, Edinburgh.
Antitumor 50 mg/day Duke, 1992 *
Antitumor (GI) not available Duke, 1992 *
Antitumor (Kidney) 400-7,000 mg/day Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill
Livinston, Edinburgh.
Antitumor (Prostate) 400-7,000 mg/day Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill
Livinston, Edinburgh.
Bacteristat not available Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Bruchiphobe not available Duke, 1992 *
Cancer-Preventive 5-25 ug/ml Gawron, A. and Glowniak, K. 1987. Cytostatic Activity of Coumarins in vitro. Planta Medica 1987: 526.
Carcinogenic 200 mg/kg orl mus Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill
Livinston, Edinburgh.
Cardiodepressant not available Duke, 1992 *
Cardiotonic not available Duke, 1992 *
Chemopreventive not available Duke, 1992 *
DME-Inhibitor IC50=57.5 uM Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 134.
Emetic not available Duke, 1992 *
Estrogenic not available Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Fungicide not available Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Hemorrhagic not available Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Hepatotoxic 100 mg/kg dog Duke, 1992 *
List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name Plant Part Low Parts Per Million High Parts Per Million Standard Deviation Reference
Acacia farnesiana Plant not available not available not available Pakistan Encyclopedia Planta Medica. 1986.
Acacia farnesiana Flower not available not available not available Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
Ageratum conyzoides Plant not available not available not available List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Ageratum conyzoides Shoot not available 1040.0 -1.0 R. Vera, (1993); Chemical composition of the essential oil Ageratum conyzoides L. (Asteraceae) from Reunion, Flavour Fragr. J., Vol.8, 257-260.
Aloe vera Plant not available not available not available Pakistan Encyclopedia Planta Medica. 1986.
Althaea officinalis Shoot not available not available not available Duke, 1992 *
Althaea officinalis Root not available not available not available Duke, 1992 *
Ammi visnaga Plant not available not available not available Duke, 1992 *
Apium graveolens Plant not available not available not available Duke, 1992 *
Artemisia annua Plant not available not available not available Father Nature's Farmacy: The aggregate of all these three-letter citations.
Artemisia annua Shoot not available not available not available Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Artemisia capillaris Plant not available not available not available Duke, 1992 *
Artemisia dracunculus Plant not available not available not available Duke, 1992 *
Artemisia vulgaris Plant not available not available not available Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp.
Astragalus membranaceus Root not available not available not available Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Capparis spinosa Plant not available not available not available Duke, 1992 *
Cichorium intybus Plant not available not available not available Duke, 1992 *
Cinnamomum aromaticum Bark not available not available not available Duke, 1992 *
Cinnamomum verum Bark not available not available not available Duke, 1992 *
Cinnamomum verum Leaf Essent. Oil not available not available not available Duke, 1992 *