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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Topoisomerase-I-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
XESTOQUINONE IC50=0.15 ug/ml Bae, M. A., Tsuji, T., Kondo, K., Hirase, T., Ishibashi, M., Shigemori, H., Kobayashi, J. I. 1993. Inhibition of Mammalian Topoisomerase I by Xestoquinone and Halenaquinone. Biosci. Biotech. Biochem., 57: 330-331.
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List of Activity Plants.
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Plant Name Common Name Chemical Count Total Parts Per Million
Artemisia annua Qinghao; Sweet Annie; Annual Mugwort (GRIN); Annual Wormwood (GRIN); Sweet Wormwood (GRIN) 4 0
Artemisia dracunculus Tarragon 5 97
Artocarpus altilis Breadfruit 1 0
Artocarpus heterophyllus Jackfruit 1 0
Asimina triloba Pawpaw 1 0
Aspalathus linearis Rooibos; Kaffree Tea; Red Bush Tea 3 264, 055.7999997139
Asparagus officinalis Asparagus 2 0
Astragalus membranaceus Huang-Chi; Huang Qi 3 0
Avena sativa Oats 1 620
Azadirachta indica Neem 3 5, 000
Ballota nigra Black Horehound 2 0
Baptisia sp 1 0
Baptisia tinctoria Wild Indigo 3 0
Barosma betulina Buchu 1 0
Basella alba Vinespinach 1 0
Berberis vulgaris Barberry 2 0
Beta vulgaris Beet; Beetroot; Sugar Beet; Garden Beet 2 0
Bocconia arborea Tree Poppy 1 0
Bocconia frutescens Tree Poppy 1 0
Borago officinalis Borage; Beebread; Beeplant; Talewort 2 0