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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Topoisomerase-I-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
XESTOQUINONE IC50=0.15 ug/ml Bae, M. A., Tsuji, T., Kondo, K., Hirase, T., Ishibashi, M., Shigemori, H., Kobayashi, J. I. 1993. Inhibition of Mammalian Topoisomerase I by Xestoquinone and Halenaquinone. Biosci. Biotech. Biochem., 57: 330-331.
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List of Activity Plants.
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Plant Name Common Name Chemical Count Total Parts Per Million
Cimicifuga racemosa Black Cohosh; Black Snakeroot 2 0
Cinnamomum camphora Camphor; Ho Leaf 2 0
Citrus aurantium Petitgrain; Bitter Orange 1 0
Citrus limon Lemon 4 100
Citrus paradisi Grapefruit 4 58
Citrus sinensis Orange 4 45, 943.90000021458
Clitoria falcata 1 0
Clitoria ternatea 1 50
Cnicus benedictus Blessed Thistle 1 0
Coffea arabica Coffee 1 64, 000
Cola acuminata Abata Cola 2 50, 000
Colchicum autumnale Autumn Crocus; Meadow Saffron 1 0
Cologana broussonetii 1 0
Commiphora wightii Guggul; Indian Bdellium-Tree 1 0
Consolida ajacis Larkspur 2 0
Conyza canadensis Butterweed; Hogweed; Horseweed 2 0
Coptis spp Generic Goldthread 1 0
Coriandrum sativum Coriander; Chinese Parsley; Cilantro 2 0
Coriaria myrtifolia Mealy Tree 2 0
Coriaria thymifolia Ground Toot; Shanshi 2 0