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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Topoisomerase-I-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
XESTOQUINONE IC50=0.15 ug/ml Bae, M. A., Tsuji, T., Kondo, K., Hirase, T., Ishibashi, M., Shigemori, H., Kobayashi, J. I. 1993. Inhibition of Mammalian Topoisomerase I by Xestoquinone and Halenaquinone. Biosci. Biotech. Biochem., 57: 330-331.
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List of Activity Plants.
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Plant Name Common Name Chemical Count Total Parts Per Million
Tridax procumbens Coatbuttons; Mexican daisy 2 0
Trifolium alexandrinum 1 0
Trifolium brachycalycinum 1 25, 800
Trifolium hybridum 1 0
Trifolium pratense Red Clover; Purple Clover; Peavine Clover; Cowgrass 7 93, 176
Trifolium repens 1 0
Trifolium sp 1 0
Trifolium subterraneum 1 27, 000
Trigonella foenum-graecum Fenugreek; Greek Clover; Greek Hay; Bockshornklee (Ger.); Alholva (Sp.) 6 100
Triticum aestivum Wheat 2 0
Tsuga canadensis Eastern Hemlock 1 0
Turnera diffusa Damiana 1 0
Tussilago farfara Coltsfoot 2 0
Ulex micranthus 1 0
Ulex sp 1 0
Uncaria catechu Gambir; Pale Catechu 2 0
Uncaria guianensis Cat's Claw; Una de Gato; Garabato Colorado; Tambor Huasca; Ungunagi 1 0
Urginea maritima European Squill 2 0
Urtica dioica European Nettle; Stinging Nettle 3 0
Vaccinium corymbosum Blueberry 3 0