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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Topoisomerase-I-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
XESTOQUINONE IC50=0.15 ug/ml Bae, M. A., Tsuji, T., Kondo, K., Hirase, T., Ishibashi, M., Shigemori, H., Kobayashi, J. I. 1993. Inhibition of Mammalian Topoisomerase I by Xestoquinone and Halenaquinone. Biosci. Biotech. Biochem., 57: 330-331.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Santolina chamaecyparissus Lavender Cotton 1 0
Satureja montana Winter Savory; Savory 2 0
Schinus molle California Peppertree; Mastic-Tree; Peruvian Peppertree 5 0
Schinus terebinthifolius Brazilian Peppertree 3 0
Scutellaria baicalensis Chinese Skullcap; Huang Qin; Baikal Skullcap 2 2, 700
Scutellaria galericulata Marsh Skullcap 3 0
Scutellaria lateriflora Mad-Dog Skullcap; Scullcap 2 0
Senna occidentalis Coffee Senna 1 0
Serenoa repens Saw Palmetto; Scrub-Palmetto 2 0
Silybum marianum Milk Thistle; Lady's Thistle 5 0
Solanum tuberosum Potato 5 0
Solidago gigantea Early Goldenrod 2 0
Solidago virgaurea European Goldenrod; Woundwort 1 0
Sophora angustifolia Narrowleaf Sophora 1 0
Sophora flavescens Shrubby Sophora; Ku Shen 1 0
Sophora japonica Japanese Pagoda Tree 4 0
Sophora subprostrata Shan Dou Gen 2 0
Sorbus aucubaria Rowan Berry 2 0
Spartium junceum Genet; Spanish Broom; Weaver's Broom 3 0
Spinacia oleracea Spinach 2 40