Biological Activity Lipoxygenase-Inhibitor | Dr. Duke's Phytochemical and Ethnobotanical Databases

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name	Dosage	Reference
POLYPHENOLS	not available	Duke, 1992 *
PROCYANIDIN-D2	IC29=1.25 mM	Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
QUERCETIN	IC11=1.25 mM	Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
QUERCETIN	IC50=0.1-5 uM	Duke, 1992 *
ROSMARINIC-ACID	not available	Duke, 1992 *
RUTIN	IC75=2.5 mM	Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
SCANDENOLIDE	IC50=30-60uM	Duke, 1992 *
SQUALENE	not available	Chemical Express, 7: 297, 1992.
TANNIN	not available	Duke, 1992 *
TAXIFOLIN	not available	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
THEAFLAVIN	IC50=3,604 uM	Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
THEAFLAVIN-DIGALLATE	IC50=0.25 uM	Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
THEAFLAVIN-MONOGALLATE-B	IC50=0.62 uM	Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
THYMOQUINONE	IC50 1 ug/ml	Houghton, P.J., Zarka, R., Heras, B., and Hoult, J.R.S. 1994. Fixed Oil of Nigella sativa and Derived Thymoquinone Inhibit Eicosanoid Generation in Leukocytes and Membrane Lipid Peroxidation. Planta Medica, 61: 33.
TOCOPHEROL	not available	Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
UMBELLIFERONE	not available	Duke, 1992 *
URSOLIC-ACID	IC50=0.18 mM	Duke, 1992 *
URUSHIOL	not available	Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
UVAOL	not available	Duke, 1992 *
VERBASCOSIDE	not available	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.

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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name	Common Name	Chemical Count	Total Parts Per Million
Consolida ajacis	Larkspur	2	0
Convallaria majalis	Lily-Of-The-Valley	3	0
Conyza canadensis	Butterweed; Hogweed; Horseweed	2	0
Coptis chinensis	Chinese Goldthread; Huang-Lian; Huang-Lien	1	270, 000
Coptis japonica	Huang-Lia; Huang-Lian; Huang-Lien; Japanese Goldthread	1	280, 000
Coptis spp	Generic Goldthread	2	90, 000
Corchorus olitorius	Jew's Mallow; Mulukiya; Nalta Jute	1	0
Coriandrum sativum	Coriander; Chinese Parsley; Cilantro	8	5, 748.30000000447
Coriaria myrtifolia	Mealy Tree	2	200, 000
Coriaria thymifolia	Ground Toot; Shanshi	1	0
Cornus florida	American Dogwood	4	30, 000
Cornus mas	Cornelian Cherry; Sorbet	4	0
Cornus officinalis	Chinese Dogwood	1	0
Corydalis spp	Fumewort	1	0
Corylus americana	American Filbert; American Hazel	1	0
Corylus avellana	English Filbert; European Filbert; European Hazel; Hazel; Cobnut	3	0
Crataegus cuneata	Hawthorn	3	0
Crataegus laevigata	Hawthorn; English Hawthorn; Whitethorn; Woodland Hawthorn	11	0
Crataegus monogyna	Hawthorn; English Hawthorn	9	80
Crataegus pentagyna	Hawthorn	2	0