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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antiplasmodial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
ISOFEBRIFUGINE IC50=0.002-0.003 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOIGUESTEROL IC50=0.023-0.54 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOMELDENIN IC50=50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOSTRYCHNINE IC50=14->20 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOSUNGUCINE IC50=0.3-1.3 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ISOTETRANDRINE IC50=100 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
JATRORRHIZINE IC50=0.42-1.61 ug/ml *
JATRORRHIZINE-CHLORIDE IC50= 0.36ug/ml *
KORUNDAMINE-A IC50=1.1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
KORUPENSAMINE-A IC50=0.02-0.6 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
KORUPENSAMINE-B IC50=0.2-0.4 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
KORUPENSAMINE-E IC50=2 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
LICOCHALCONE-A *
LIMACINE IC50=0.05-0.79 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
LYCORINE IC50=0.3-0.7 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
MAACKIAIN EC50=10 ug/ml Chanphen, R., Thebtaranonth, Y., Wanauppathamkul, S., and Yuthavong, Y. 1998. Antimalarial Principles from Artemisia indica. J. Nat. Prod., 61 (9):1146-1147.
MACRALSTONINE IC50=8.9 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
MACROCARPAMINE IC50=0.4-32.6 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
MELDENIN IC50=5.2 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
METHYLANGOLENSATE IC50=5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Thymus serpyllum Creeping Thyme 2 13, 900
Thymus vulgaris Common Thyme; Garden Thyme; Thyme 2 75, 300
Thymus zygis Spanish Thyme 1 0
Tilia sp. Basswood; Lime; Linden 1 0
Tovomita brasiliensis 1 0
Tovomita excelsa 1 83.9000015258789
Tovomita mangle 1 0
Tovomita pyrifolia 1 0
Triadenum japonicum 1 0
Tribulus terrestris Puncture-vine 1 0
Tridax procumbens Coatbuttons; Mexican daisy 1 0
Trifolium pratense Red Clover; Purple Clover; Peavine Clover; Cowgrass 2 168
Trigonella foenum-graecum Fenugreek; Greek Clover; Greek Hay; Bockshornklee (Ger.); Alholva (Sp.) 1 0
Tripterygium wilfordiim Yellow Vine 1 0
Triticum aestivum Wheat 1 0
Tussilago farfara Coltsfoot 1 0
Umbellularia californica California Bay 1 40
Uncaria catechu Gambir; Pale Catechu 2 0
Uncaria guianensis Cat's Claw; Una de Gato; Garabato Colorado; Tambor Huasca; Ungunagi 1 0
Uncaria tomentosa Cat's Claw; Garabato Amarillo; Una de Gato 3 4, 980