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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
BRUCEINE-A IC50=0.005-0.011 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BRUCEINE-A IC50=11 ng/ml Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
BRUCEINE-B IC50=0.023-0.5 uM *
BRUCEINE-B IC50=0.005-0.011 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BRUCEINE-B IC50=11 ng/ml Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
BRUCEINE-C IC50=0.009 uM *
BRUCEINE-C IC50=0.005-0.011 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BRUCEINE-C IC50=0.5 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BRUCEINE-C IC50=5 ng/ml Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
BRUCEINE-D IC50=0.037-0.5 uM *
BRUSATOL IC50=0.006 uM *
CARYOPHYLLENE-16-ALPHA-OXIDE IC50=345 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CARYOPHYLLENE-ALPHA-OXIDE EC50=>3-100 uM *
CASTICIN (Synergic w artemisinin) *
CASTICIN IC50=24 uM *
CEDRELONE IC50=0.77 ug/ml Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982.
CEDRONIN IC50=0.23-0.25 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CELASTROL IC50=0.181-0.254 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CEPHAELINE IC50=0.011-0.027 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CHAPARRINONE IC50=0.037 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Lycoris squamigera Magic Lily; Resurrection Lily 1 0
Lythrum salicaria Purple Loosestrife 1 0
Machaerocereus gummosus 1 4, 000
Macleaya cordata Plume Poppy 1 0
Maclura pomifera Osage-Orange; Hedge Apple 4 7, 928
Madhuca microphylla 1 930
Madhuca nerifolia 1 560
Magnolia denudata Hsin-I; Xin-Yi 3 0
Magnolia kobus Hsin-I; Xin-Yi 2 1, 000
Magnolia officinalis Chinese Magnolia; Hou Pu; Magnolia-Bark 1 0
Mahonia aquifolium Oregon Grape; Blue Barberry; Holly Barberry; Holly Mahonia; Mountain Grape 8 195
Mahonia bealei 1 5, 000
Mahonia fargesii 3 0
Mahonia fortunei 2 0
Mahonia gracilipes 4 0
Mahonia japonica Japanese Ashberry; Hiiragi-Nanten 4 0
Mahonia nervosa Oregon Barberry; Oregon Grape-Holly; Oregon Grape; Water Holly 1 0
Mahonia philipinensis 2 0
Mahonia repens Creeping Barberry; Oregon Barberry; Oregon Grape-Holly; Oregon Grape 6 11, 588
Mahonia siamensis 2 4, 600