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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
BRUCEINE-A IC50=11 ng/ml Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
BRUCEINE-A IC50=0.021-0.5 uM *
BRUCEINE-B IC50=0.005-0.011 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BRUCEINE-B IC50=11 ng/ml Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
BRUCEINE-B IC50=0.023-0.5 uM *
BRUCEINE-C IC50=0.009 uM *
BRUCEINE-C IC50=0.005-0.011 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BRUCEINE-C IC50=5 ng/ml Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
BRUCEINE-C IC50=0.5 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BRUCEINE-D IC50=0.037-0.5 uM *
BRUSATOL IC50=0.006 uM *
CARYOPHYLLENE-16-ALPHA-OXIDE IC50=345 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CARYOPHYLLENE-ALPHA-OXIDE EC50=>3-100 uM *
CASTICIN (Synergic w artemisinin) *
CASTICIN IC50=24 uM *
CEDRELONE IC50=0.77 ug/ml Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982.
CEDRONIN IC50=0.23-0.25 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CELASTROL IC50=0.181-0.254 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CEPHAELINE IC50=0.011-0.027 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CHAPARRINONE IC50=0.037 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Malus domestica Apple 5 149, 189
Mangifera indica Mango 1 0
Maranta arundinacea Arrowroot; Bermuda Arrowroot 1 0
Marrubium vulgare Horehound; White Horehound 2 4, 400
Matricaria recutita Annual Camomile; German Camomile; Wild Camomile 4 0
Maytenus aquifolium 1 0
Maytenus canariensis 1 0
Medicago sativa Alfalfa; Lucerne 1 0
Melaleuca alternifolia Teatree 1 12
Melaleuca leucadendra Cajeput 3 0
Melaleuca leucadendron 1 420
Melanoxylon brauna 1 250
Melia azedarach Chinaberry 6 0
Melilotus officinalis Yellow Sweetclover 2 0
Melissa officinalis Balm; Lemonbalm; Melissa; Bee Balm 3 0
Menispermum canadense Moonseed 1 0
Mentha aquatica Water Mint 1 0
Mentha longifolia Biblical Mint 2 135
Mentha spicata Spearmint; Hortela da Folha Miuda 4 0
Mentha x piperita Peppermint 4 5.019999999552965